BRD-K16444452_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K16444452_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARMCX2 armadillo repeat containing, X-linked 2
ATG3 autophagy related 3
C3ORF14 chromosome 3 open reading frame 14
CKAP4 cytoskeleton-associated protein 4
CLIC4 chloride intracellular channel 4
CTSZ cathepsin Z
EXT1 exostosin glycosyltransferase 1
GLUL glutamate-ammonia ligase
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GRB14 growth factor receptor-bound protein 14
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HYOU1 hypoxia up-regulated 1
IGHD immunoglobulin heavy constant delta
IGLL1 immunoglobulin lambda-like polypeptide 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KRT81 keratin 81, type II
KYNU kynureninase
MAP7 microtubule-associated protein 7
NARF nuclear prelamin A recognition factor
NPTX2 neuronal pentraxin II
PALLD palladin, cytoskeletal associated protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PROM1 prominin 1
RAB5C RAB5C, member RAS oncogene family
RGCC regulator of cell cycle
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
SCGB2A1 secretoglobin, family 2A, member 1
SFRP1 secreted frizzled-related protein 1
SORBS2 sorbin and SH3 domain containing 2
TMEM45A transmembrane protein 45A

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
CCNB1 cyclin B1
CCR7 chemokine (C-C motif) receptor 7
CD36 CD36 molecule (thrombospondin receptor)
CDC42 cell division cycle 42
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5A eukaryotic translation initiation factor 5A
EPHA3 EPH receptor A3
FAM65B family with sequence similarity 65, member B
FBN2 fibrillin 2
FERMT2 fermitin family member 2
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
FOXO1 forkhead box O1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HCAR3 hydroxycarboxylic acid receptor 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL6ST interleukin 6 signal transducer
IL7R interleukin 7 receptor
NRN1 neuritin 1
PLBD1 phospholipase B domain containing 1
PLS3 plastin 3
QKI QKI, KH domain containing, RNA binding
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TLR4 toll-like receptor 4
WSB1 WD repeat and SOCS box containing 1
XAF1 XIAP associated factor 1
ZNF586 zinc finger protein 586
ZNF587 zinc finger protein 587
ZNF91 zinc finger protein 91