BRD-K16189898_CHIR-99021_MDAMB231_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K16189898_CHIR-99021_MDAMB231_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ANKRD10 ankyrin repeat domain 10
BRD2 bromodomain containing 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
COL3A1 collagen, type III, alpha 1
EFNB2 ephrin-B2
NKTR natural killer cell triggering receptor
ODC1 ornithine decarboxylase 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SOX4 SRY (sex determining region Y)-box 4
SRPRB signal recognition particle receptor, B subunit
SRRM2 serine/arginine repetitive matrix 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADAM10 ADAM metallopeptidase domain 10
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ASS1 argininosuccinate synthase 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CCND2 cyclin D2
CD9 CD9 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CRISP3 cysteine-rich secretory protein 3
CSRP2 cysteine and glycine-rich protein 2
CTGF connective tissue growth factor
DEPTOR DEP domain containing MTOR-interacting protein
DKK3 dickkopf WNT signaling pathway inhibitor 3
DST dystonin
ETV1 ets variant 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FZD2 frizzled class receptor 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GSTA1 glutathione S-transferase alpha 1
IFI16 interferon, gamma-inducible protein 16
IGF1R insulin-like growth factor 1 receptor
KRT17 keratin 17, type I
LCN2 lipocalin 2
MAOB monoamine oxidase B
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1X metallothionein 1X
MYLK myosin light chain kinase
OLFM4 olfactomedin 4
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEX11A peroxisomal biogenesis factor 11 alpha
PRKCDBP protein kinase C, delta binding protein
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
TMEM30B transmembrane protein 30B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
WNT5A wingless-type MMTV integration site family, member 5A