BRD-K16189898_CHIR-99021_MCF7_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

106 genes differentially expressed following the BRD-K16189898_CHIR-99021_MCF7_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANOS1 anosmin 1
BCL2A1 BCL2-related protein A1
BHLHE40 basic helix-loop-helix family, member e40
BTG3 BTG family, member 3
CA2 carbonic anhydrase II
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
CXCL14 chemokine (C-X-C motif) ligand 14
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
EGR1 early growth response 1
EMP3 epithelial membrane protein 3
ENO1 enolase 1, (alpha)
EPHB2 EPH receptor B2
F3 coagulation factor III (thromboplastin, tissue factor)
FASTKD5 FAST kinase domains 5
FHL1 four and a half LIM domains 1
HBEGF heparin-binding EGF-like growth factor
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFRD1 interferon-related developmental regulator 1
ITM2C integral membrane protein 2C
KCTD12 potassium channel tetramerization domain containing 12
KLF10 Kruppel-like factor 10
LGALS1 lectin, galactoside-binding, soluble, 1
LRP4 low density lipoprotein receptor-related protein 4
MMP9 matrix metallopeptidase 9
MT1M metallothionein 1M
ODC1 ornithine decarboxylase 1
PLBD1 phospholipase B domain containing 1
PSAP prosaposin
RPL37A ribosomal protein L37a
SATB2 SATB homeobox 2
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TOB1 transducer of ERBB2, 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TUBB2B tubulin, beta 2B class IIb
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AKAP7 A kinase (PRKA) anchor protein 7
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARID5B AT rich interactive domain 5B (MRF1-like)
BEX1 brain expressed, X-linked 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CCNF cyclin F
CD200 CD200 molecule
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL1A2 collagen, type I, alpha 2
DEFB1 defensin, beta 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
EPB41L1 erythrocyte membrane protein band 4.1-like 1
ETV1 ets variant 1
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FTO fat mass and obesity associated
HMGA2 high mobility group AT-hook 2
IGFBP5 insulin-like growth factor binding protein 5
JADE2 jade family PHD finger 2
KRAS Kirsten rat sarcoma viral oncogene homolog
LDB2 LIM domain binding 2
LOC100505650 uncharacterized LOC100505650
LTF lactotransferrin
MAN1A1 mannosidase, alpha, class 1A, member 1
MAST4 microtubule associated serine/threonine kinase family member 4
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYLK myosin light chain kinase
MYO5C myosin VC
NID2 nidogen 2 (osteonidogen)
NPY1R neuropeptide Y receptor Y1
NRN1 neuritin 1
NT5E 5'-nucleotidase, ecto (CD73)
NUP62 nucleoporin 62kDa
OXA1L oxidase (cytochrome c) assembly 1-like
PBX1 pre-B-cell leukemia homeobox 1
PDZK1 PDZ domain containing 1
PEG10 paternally expressed 10
PXDN peroxidasin
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERINC5 serine incorporator 5
SH3BP4 SH3-domain binding protein 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A46 solute carrier family 25, member 46
SLC38A2 solute carrier family 38, member 2
SNAP25 synaptosomal-associated protein, 25kDa
SORBS2 sorbin and SH3 domain containing 2
STC1 stanniocalcin 1
SULF1 sulfatase 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCF4 transcription factor 4
TERF2 telomeric repeat binding factor 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TPM4 tropomyosin 4
TSPYL5 TSPY-like 5
VAV3 vav 3 guanine nucleotide exchange factor
ZNF451 zinc finger protein 451