BRD-K16189898_CHIR-99021_HEPG2_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K16189898_CHIR-99021_HEPG2_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
BGN biglycan
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ECM1 extracellular matrix protein 1
EMP1 epithelial membrane protein 1
FOSL1 FOS-like antigen 1
GEM GTP binding protein overexpressed in skeletal muscle
GPRC5A G protein-coupled receptor, class C, group 5, member A
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HOPX HOP homeobox
MCTP1 multiple C2 domains, transmembrane 1
MECOM MDS1 and EVI1 complex locus
MMP12 matrix metallopeptidase 12
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCDH9 protocadherin 9
PELI1 pellino E3 ubiquitin protein ligase 1
PTN pleiotrophin
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A2 S100 calcium binding protein A2
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPARCL1 SPARC-like 1 (hevin)
SPINK1 serine peptidase inhibitor, Kazal type 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
XIST X inactive specific transcript (non-protein coding)
ZEB1 zinc finger E-box binding homeobox 1

decreased expression

Symbol Name
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLVRA biliverdin reductase A
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CD44 CD44 molecule (Indian blood group)
CDC25B cell division cycle 25B
CHMP4A charged multivesicular body protein 4A
CLDN10 claudin 10
COL1A1 collagen, type I, alpha 1
CRYAB crystallin, alpha B
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF5A eukaryotic translation initiation factor 5A
ERBB2 erb-b2 receptor tyrosine kinase 2
FABP4 fatty acid binding protein 4, adipocyte
FOLR1 folate receptor 1 (adult)
FST follistatin
GPX3 glutathione peroxidase 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
KDM5D lysine (K)-specific demethylase 5D
MDK midkine (neurite growth-promoting factor 2)
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NREP neuronal regeneration related protein
PCNA proliferating cell nuclear antigen
PDGFC platelet derived growth factor C
PDZD2 PDZ domain containing 2
RBKS ribokinase
RBP4 retinol binding protein 4, plasma
S100P S100 calcium binding protein P
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
TYMS thymidylate synthetase
VCAN versican
WNT5A wingless-type MMTV integration site family, member 5A