BRD-K16189898_CHIR-99021_BT20_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K16189898_CHIR-99021_BT20_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA12 carbonic anhydrase XII
FOLR1 folate receptor 1 (adult)
HACD3 3-hydroxyacyl-CoA dehydratase 3
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
MLF1 myeloid leukemia factor 1
PGC progastricsin (pepsinogen C)
PI3 peptidase inhibitor 3, skin-derived
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
RPIA ribose 5-phosphate isomerase A
SET SET nuclear proto-oncogene
SOX9 SRY (sex determining region Y)-box 9
SYNE2 spectrin repeat containing, nuclear envelope 2
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAMBI BMP and activin membrane-bound inhibitor
C3ORF14 chromosome 3 open reading frame 14
CCNG2 cyclin G2
CDC45 cell division cycle 45
CPE carboxypeptidase E
DMD dystrophin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
F13A1 coagulation factor XIII, A1 polypeptide
GADD45B growth arrest and DNA-damage-inducible, beta
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MMP7 matrix metallopeptidase 7
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1X metallothionein 1X
NAV2 neuron navigator 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
OPN3 opsin 3
POSTN periostin, osteoblast specific factor
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
TCF4 transcription factor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10