BRD-K15592317_CP466722_SKBR3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K15592317_CP466722_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
AGR2 anterior gradient 2
ANXA6 annexin A6
APOD apolipoprotein D
ASNS asparagine synthetase (glutamine-hydrolyzing)
DDIT4 DNA-damage-inducible transcript 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DPT dermatopontin
EXPH5 exophilin 5
FABP4 fatty acid binding protein 4, adipocyte
FGFR1 fibroblast growth factor receptor 1
GOLM1 golgi membrane protein 1
GPM6B glycoprotein M6B
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HOPX HOP homeobox
HOXA5 homeobox A5
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
ISG15 ISG15 ubiquitin-like modifier
KIAA1033 KIAA1033
LGALS1 lectin, galactoside-binding, soluble, 1
MAST2 microtubule associated serine/threonine kinase 2
MX1 MX dynamin-like GTPase 1
NUPR1 nuclear protein, transcriptional regulator, 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PHGDH phosphoglycerate dehydrogenase
PLAGL1 pleiomorphic adenoma gene-like 1
PSAT1 phosphoserine aminotransferase 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
S100P S100 calcium binding protein P
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SKAP2 src kinase associated phosphoprotein 2
SLC38A1 solute carrier family 38, member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRPX sushi-repeat containing protein, X-linked
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TNNT1 troponin T type 1 (skeletal, slow)
TRIM22 tripartite motif containing 22
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
AHSG alpha-2-HS-glycoprotein
AKAP12 A kinase (PRKA) anchor protein 12
APOA2 apolipoprotein A-II
APOC1 apolipoprotein C-I
C3 complement component 3
CD58 CD58 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES1 carboxylesterase 1
CLU clusterin
CP ceruloplasmin (ferroxidase)
CPB1 carboxypeptidase B1 (tissue)
CXADR coxsackie virus and adenovirus receptor
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS3 dehydrogenase/reductase (SDR family) member 3
EBP emopamil binding protein (sterol isomerase)
FOXG1 forkhead box G1
HIST1H1C histone cluster 1, H1c
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPA4 heat shock 70kDa protein 4
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
JADE2 jade family PHD finger 2
KIAA1598
KLK10 kallikrein-related peptidase 10
KRT13 keratin 13, type I
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MCOLN1 mucolipin 1
NT5E 5'-nucleotidase, ecto (CD73)
PSD3 pleckstrin and Sec7 domain containing 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RIPK4 receptor-interacting serine-threonine kinase 4
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
TFRC transferrin receptor
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TSPAN8 tetraspanin 8