BRD-K15467014_3-(2,8-dinitro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine oxalate KCR-18_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K15467014_3-(2,8-dinitro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine oxalate KCR-18_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AGR2 anterior gradient 2
ALDOC aldolase C, fructose-bisphosphate
ANXA1 annexin A1
AQP3 aquaporin 3 (Gill blood group)
CRISP3 cysteine-rich secretory protein 3
CSTA cystatin A (stefin A)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GSN gelsolin
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INSIG1 insulin induced gene 1
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA6 integrin, alpha 6
ITM2A integral membrane protein 2A
KLHL9 kelch-like family member 9
KRT15 keratin 15, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTBP1 latent transforming growth factor beta binding protein 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN1C1 mannosidase, alpha, class 1C, member 1
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
MTUS1 microtubule associated tumor suppressor 1
NDRG2 NDRG family member 2
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
PDGFC platelet derived growth factor C
S100P S100 calcium binding protein P
SLCO3A1 solute carrier organic anion transporter family, member 3A1
STC2 stanniocalcin 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBI transforming growth factor, beta-induced, 68kDa
TIAM1 T-cell lymphoma invasion and metastasis 1

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
CHL1 cell adhesion molecule L1-like
FASN fatty acid synthase
GSE1 Gse1 coiled-coil protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHM immunoglobulin heavy constant mu
MAP1B microtubule-associated protein 1B
MME membrane metallo-endopeptidase
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
SCG2 secretogranin II
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TPM4 tropomyosin 4
TWIST1 twist family bHLH transcription factor 1