BRD-K15467014_3-(2,8-dinitro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine oxalate KCR-18_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

80 genes differentially expressed following the BRD-K15467014_3-(2,8-dinitro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine oxalate KCR-18_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAMBI BMP and activin membrane-bound inhibitor
C5AR1 complement component 5a receptor 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CXCL11 chemokine (C-X-C motif) ligand 11
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EGFL6 EGF-like-domain, multiple 6
EPAS1 endothelial PAS domain protein 1
FADS1 fatty acid desaturase 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
FGG fibrinogen gamma chain
FST follistatin
GPC3 glypican 3
GSTA1 glutathione S-transferase alpha 1
GSTA4 glutathione S-transferase alpha 4
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INSIG1 insulin induced gene 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LDLR low density lipoprotein receptor
LIMCH1 LIM and calponin homology domains 1
LYZ lysozyme
MSMO1 methylsterol monooxygenase 1
NGRN neugrin, neurite outgrowth associated
PCDH9 protocadherin 9
PTN pleiotrophin
RPS4Y1 ribosomal protein S4, Y-linked 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A12 S100 calcium binding protein A12
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCPEP1 serine carboxypeptidase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SQLE squalene epoxidase
TARP TCR gamma alternate reading frame protein
TBX2 T-box 2
TMEM97 transmembrane protein 97

decreased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BHLHE41 basic helix-loop-helix family, member e41
C1QTNF3 C1q and tumor necrosis factor related protein 3
CCL2 chemokine (C-C motif) ligand 2
CPB1 carboxypeptidase B1 (tissue)
DCLK1 doublecortin-like kinase 1
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DEFB1 defensin, beta 1
DEGS1 delta(4)-desaturase, sphingolipid 1
ESR1 estrogen receptor 1
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GLIPR1 GLI pathogenesis-related 1
ITGB1BP1 integrin beta 1 binding protein 1
KRT7 keratin 7, type II
LOC100505650 uncharacterized LOC100505650
MFAP5 microfibrillar associated protein 5
MMP13 matrix metallopeptidase 13
MT1E metallothionein 1E
MYOF myoferlin
NNMT nicotinamide N-methyltransferase
PDGFA platelet-derived growth factor alpha polypeptide
PHLDA2 pleckstrin homology-like domain, family A, member 2
RBP1 retinol binding protein 1, cellular
RUNX3 runt-related transcription factor 3
S100A2 S100 calcium binding protein A2
SCGB2A2 secretoglobin, family 2A, member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPON1 spondin 1, extracellular matrix protein
THBS1 thrombospondin 1
TM9SF3 transmembrane 9 superfamily member 3
TMEM45A transmembrane protein 45A
TXNDC9 thioredoxin domain containing 9
WFDC2 WAP four-disulfide core domain 2