BRD-K14711204_4-(4-hydroxy-2,6-dimethylheptan-4-yl)-N,N-diphenyl-1H-1,2,3-triazole-1-carboxamide_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K14711204_4-(4-hydroxy-2,6-dimethylheptan-4-yl)-N,N-diphenyl-1H-1,2,3-triazole-1-carboxamide_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AHNAK2 AHNAK nucleoprotein 2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CA12 carbonic anhydrase XII
CD24 CD24 molecule
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLCA2 chloride channel accessory 2
CRABP2 cellular retinoic acid binding protein 2
DEFB1 defensin, beta 1
IL1RN interleukin 1 receptor antagonist
KCNK1 potassium channel, two pore domain subfamily K, member 1
KRT16 keratin 16, type I
KRT6B keratin 6B, type II
MMP1 matrix metallopeptidase 1
PI3 peptidase inhibitor 3, skin-derived
PLK2 polo-like kinase 2
PROM1 prominin 1
RHCG Rh family, C glycoprotein
S100A12 S100 calcium binding protein A12
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
SCAND1 SCAN domain containing 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFN stratifin
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLPI secretory leukocyte peptidase inhibitor
SPRR1B small proline-rich protein 1B
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
CDK6 cyclin-dependent kinase 6
CEMIP cell migration inducing protein, hyaluronan binding
CTTN cortactin
DHRS2 dehydrogenase/reductase (SDR family) member 2
ELOVL5 ELOVL fatty acid elongase 5
LAPTM4B lysosomal protein transmembrane 4 beta
MXRA5 matrix-remodelling associated 5
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP4 secreted frizzled-related protein 4