BRD-K14711204_4-(4-hydroxy-2,6-dimethylheptan-4-yl)-N,N-diphenyl-1H-1,2,3-triazole-1-carboxamide_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K14711204_4-(4-hydroxy-2,6-dimethylheptan-4-yl)-N,N-diphenyl-1H-1,2,3-triazole-1-carboxamide_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
CORO1C coronin, actin binding protein, 1C
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
EGR1 early growth response 1
FADS1 fatty acid desaturase 1
FDPS farnesyl diphosphate synthase
FOSL1 FOS-like antigen 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LTF lactotransferrin
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP7 matrix metallopeptidase 7
MSMO1 methylsterol monooxygenase 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRPF4 pre-mRNA processing factor 4
RBM47 RNA binding motif protein 47
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SQLE squalene epoxidase
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADD3 adducin 3 (gamma)
ARMCX2 armadillo repeat containing, X-linked 2
DACH1 dachshund family transcription factor 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
HIST1H4C histone cluster 1, H4c
HP haptoglobin
LOX lysyl oxidase
SULF1 sulfatase 1
TXNIP thioredoxin interacting protein