BRD-K13662825_dinaciclib_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

90 genes differentially expressed following the BRD-K13662825_dinaciclib_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ANOS1 anosmin 1
ANPEP alanyl (membrane) aminopeptidase
ATF3 activating transcription factor 3
CADM1 cell adhesion molecule 1
CAPG capping protein (actin filament), gelsolin-like
CD9 CD9 molecule
COL11A1 collagen, type XI, alpha 1
COL1A2 collagen, type I, alpha 2
CPE carboxypeptidase E
CPM carboxypeptidase M
CTSC cathepsin C
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
EMP1 epithelial membrane protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPCAM epithelial cell adhesion molecule
EVI2A ecotropic viral integration site 2A
FBLN1 fibulin 1
FGFR3 fibroblast growth factor receptor 3
FOXF1 forkhead box F1
FRY furry homolog (Drosophila)
FST follistatin
GADD45B growth arrest and DNA-damage-inducible, beta
GPM6A glycoprotein M6A
GPNMB glycoprotein (transmembrane) nmb
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IGFBP7 insulin-like growth factor binding protein 7
ISG15 ISG15 ubiquitin-like modifier
LAMP3 lysosomal-associated membrane protein 3
MAN2A1 mannosidase, alpha, class 2A, member 1
MEIS1 Meis homeobox 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SDC4 syndecan 4
SEPP1 selenoprotein P, plasma, 1
SORT1 sortilin 1
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
THBS2 thrombospondin 2
TMSB15A thymosin beta 15a
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAG3 BCL2-associated athanogene 3
CDC25B cell division cycle 25B
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLOD4 glyoxalase domain containing 4
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
HSPA8 heat shock 70kDa protein 8
IGFBP4 insulin-like growth factor binding protein 4
JMJD6 jumonji domain containing 6
KRT10 keratin 10, type I
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT17 keratin 17, type I
LASP1 LIM and SH3 protein 1
LTF lactotransferrin
MALL mal, T-cell differentiation protein-like
MARCKSL1 MARCKS-like 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MMP7 matrix metallopeptidase 7
MRPS12 mitochondrial ribosomal protein S12
MYBPC1 myosin binding protein C, slow type
NOP56 NOP56 ribonucleoprotein
PCNA proliferating cell nuclear antigen
PDE4B phosphodiesterase 4B, cAMP-specific
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
RAE1 ribonucleic acid export 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RNPS1 RNA binding protein S1, serine-rich domain
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TSPYL5 TSPY-like 5
TXLNA taxilin alpha
USP3 ubiquitin specific peptidase 3
YBX3 Y box binding protein 3