BRD-K13580623_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K13580623_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM9 ADAM metallopeptidase domain 9
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CAV2 caveolin 2
CD24 CD24 molecule
CD9 CD9 molecule
CRABP2 cellular retinoic acid binding protein 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
DENND1B DENN/MADD domain containing 1B
EIF5 eukaryotic translation initiation factor 5
EPN2 epsin 2
FBXL12 F-box and leucine-rich repeat protein 12
FXYD6 FXYD domain containing ion transport regulator 6
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GNAS GNAS complex locus
GPM6A glycoprotein M6A
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGF1 insulin-like growth factor 1 (somatomedin C)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LAPTM5 lysosomal protein transmembrane 5
LMO3 LIM domain only 3 (rhombotin-like 2)
LOC100505650 uncharacterized LOC100505650
LPAR6 lysophosphatidic acid receptor 6
MATN2 matrilin 2
MMP2 matrix metallopeptidase 2
MYOF myoferlin
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PEA15 phosphoprotein enriched in astrocytes 15
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTPRE protein tyrosine phosphatase, receptor type, E
RAB31 RAB31, member RAS oncogene family
RGCC regulator of cell cycle
SCGB2A1 secretoglobin, family 2A, member 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SPARCL1 SPARC-like 1 (hevin)
STON1 stonin 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BEX1 brain expressed, X-linked 1
CHSY1 chondroitin sulfate synthase 1
CXCL12 chemokine (C-X-C motif) ligand 12
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FGF13 fibroblast growth factor 13
FGFR3 fibroblast growth factor receptor 3
FKBP11 FK506 binding protein 11, 19 kDa
FOLR1 folate receptor 1 (adult)
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IRS2 insulin receptor substrate 2
KDM5D lysine (K)-specific demethylase 5D
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMP5 lysosomal-associated membrane protein family, member 5
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
QDPR quinoid dihydropteridine reductase
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STC2 stanniocalcin 2
STOM stomatin
TBC1D4 TBC1 domain family, member 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TJP2 tight junction protein 2
TUBA1A tubulin, alpha 1a
UGCG UDP-glucose ceramide glucosyltransferase