BRD-K13566078_BMS-345541_MDAMB231_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

100 genes differentially expressed following the BRD-K13566078_BMS-345541_MDAMB231_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT9 acyl-CoA thioesterase 9
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKRD10 ankyrin repeat domain 10
ANXA3 annexin A3
ARPP19 cAMP-regulated phosphoprotein, 19kDa
BICD2 bicaudal D homolog 2 (Drosophila)
CAB39 calcium binding protein 39
CALML5 calmodulin-like 5
CCR7 chemokine (C-C motif) receptor 7
CD52 CD52 molecule
CD9 CD9 molecule
CDSN corneodesmosin
CXADR coxsackie virus and adenovirus receptor
DCT dopachrome tautomerase
DHCR24 24-dehydrocholesterol reductase
DSC1 desmocollin 1
DSC3 desmocollin 3
DSG1 desmoglein 1
EGFR epidermal growth factor receptor
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FILIP1L filamin A interacting protein 1-like
FLG filaggrin
GAL galanin/GMAP prepropeptide
HAL histidine ammonia-lyase
HIST1H2AC histone cluster 1, H2ac
IGHM immunoglobulin heavy constant mu
IL1R2 interleukin 1 receptor, type II
JAG1 jagged 1
KLF6 Kruppel-like factor 6
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT2 keratin 2, type II
LOR loricrin
LPIN1 lipin 1
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NMU neuromedin U
PDLIM5 PDZ and LIM domain 5
PSAT1 phosphoserine aminotransferase 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RORA RAR-related orphan receptor A
S100A7 S100 calcium binding protein A7
SFN stratifin
SLC38A2 solute carrier family 38, member 2
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
THBS2 thrombospondin 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TRIM33 tripartite motif containing 33
TUBB2A tubulin, beta 2A class IIa
TYRP1 tyrosinase-related protein 1
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
AGR2 anterior gradient 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARFIP2 ADP-ribosylation factor interacting protein 2
BHLHE41 basic helix-loop-helix family, member e41
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CRYZ crystallin, zeta (quinone reductase)
CSRP2 cysteine and glycine-rich protein 2
CYBA cytochrome b-245, alpha polypeptide
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
EDNRA endothelin receptor type A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GALE UDP-galactose-4-epimerase
GSTA1 glutathione S-transferase alpha 1
HDAC6 histone deacetylase 6
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPA1A heat shock 70kDa protein 1A
KRT13 keratin 13, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MNAT1 MNAT CDK-activating kinase assembly factor 1
MRPL12 mitochondrial ribosomal protein L12
MSRB2 methionine sulfoxide reductase B2
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NNT nicotinamide nucleotide transhydrogenase
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PRDX2 peroxiredoxin 2
PSCA prostate stem cell antigen
RPL39L ribosomal protein L39-like
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TPP1 tripeptidyl peptidase I
TSPYL5 TSPY-like 5
WFDC2 WAP four-disulfide core domain 2