BRD-K13566078_BMS-345541_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K13566078_BMS-345541_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHSG alpha-2-HS-glycoprotein
BCL2A1 BCL2-related protein A1
CD52 CD52 molecule
CDC25A cell division cycle 25A
CKB creatine kinase, brain
COCH cochlin
CSTA cystatin A (stefin A)
CTTN cortactin
CXADR coxsackie virus and adenovirus receptor
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
FASTKD5 FAST kinase domains 5
GRB14 growth factor receptor-bound protein 14
HP haptoglobin
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LY96 lymphocyte antigen 96
MAOB monoamine oxidase B
NDRG1 N-myc downstream regulated 1
NOV nephroblastoma overexpressed
PIR pirin (iron-binding nuclear protein)
PON3 paraoxonase 3
PTN pleiotrophin
QPCT glutaminyl-peptide cyclotransferase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC2 syndecan 2
SELENBP1 selenium binding protein 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SQLE squalene epoxidase
TACSTD2 tumor-associated calcium signal transducer 2
TFPI2 tissue factor pathway inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TREM1 triggering receptor expressed on myeloid cells 1
TUBA1A tubulin, alpha 1a
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
COL1A1 collagen, type I, alpha 1
CREB1 cAMP responsive element binding protein 1
DUSP4 dual specificity phosphatase 4
EFS embryonal Fyn-associated substrate
GAS1 growth arrest-specific 1
JADE2 jade family PHD finger 2
KLK6 kallikrein-related peptidase 6
OPN3 opsin 3
PDZD2 PDZ domain containing 2
PEX11A peroxisomal biogenesis factor 11 alpha
PTP4A1 protein tyrosine phosphatase type IVA, member 1
SIK1 salt-inducible kinase 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)