BRD-K13533483_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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69 genes differentially expressed following the BRD-K13533483_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ATM ATM serine/threonine kinase
AZU1 azurocidin 1
C6ORF62 chromosome 6 open reading frame 62
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLIC4 chloride intracellular channel 4
CSTA cystatin A (stefin A)
CXCL11 chemokine (C-X-C motif) ligand 11
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
ELANE elastase, neutrophil expressed
ESRP1 epithelial splicing regulatory protein 1
FAM46A family with sequence similarity 46, member A
FKBP14 FK506 binding protein 14, 22 kDa
GUSBP3 glucuronidase, beta pseudogene 3
HBB hemoglobin, beta
HEPH hephaestin
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HYOU1 hypoxia up-regulated 1
IDO1 indoleamine 2,3-dioxygenase 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ISG20 interferon stimulated exonuclease gene 20kDa
LCN2 lipocalin 2
LMO3 LIM domain only 3 (rhombotin-like 2)
MAP7 microtubule-associated protein 7
MFSD10 major facilitator superfamily domain containing 10
MT1E metallothionein 1E
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1M metallothionein 1M
MT1X metallothionein 1X
NUCB2 nucleobindin 2
PLAU plasminogen activator, urokinase
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PXDN peroxidasin
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE4 ribonuclease, RNase A family, 4
S100A6 S100 calcium binding protein A6
SDF2L1 stromal cell-derived factor 2-like 1
SNX11 sorting nexin 11
WARS tryptophanyl-tRNA synthetase
WDR61 WD repeat domain 61
ZBTB38 zinc finger and BTB domain containing 38

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CLEC2B C-type lectin domain family 2, member B
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GATA3 GATA binding protein 3
HEATR1 HEAT repeat containing 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IQGAP2 IQ motif containing GTPase activating protein 2
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
NMU neuromedin U
PALMD palmdelphin
RAI14 retinoic acid induced 14
RXRA retinoid X receptor, alpha
SCGB2A2 secretoglobin, family 2A, member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SOX11 SRY (sex determining region Y)-box 11
STC2 stanniocalcin 2
ZFP36L1 ZFP36 ring finger protein-like 1