BRD-K13390322_AT-7519_LNCAP_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

283 genes differentially expressed following the BRD-K13390322_AT-7519_LNCAP_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AAMDC adipogenesis associated, Mth938 domain containing
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AHCY adenosylhomocysteinase
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKRD36B ankyrin repeat domain 36B
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
AQP1 aquaporin 1 (Colton blood group)
AREG amphiregulin
ARL4C ADP-ribosylation factor-like 4C
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BSG basigin (Ok blood group)
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C5AR1 complement component 5a receptor 1
CADM1 cell adhesion molecule 1
CCL4 chemokine (C-C motif) ligand 4
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC42 cell division cycle 42
CETN2 centrin, EF-hand protein, 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CKB creatine kinase, brain
CLU clusterin
COL18A1 collagen, type XVIII, alpha 1
CPB1 carboxypeptidase B1 (tissue)
CRABP2 cellular retinoic acid binding protein 2
CTTN cortactin
CYB5A cytochrome b5 type A (microsomal)
CYBRD1 cytochrome b reductase 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DEFB1 defensin, beta 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DST dystonin
ECHDC2 enoyl CoA hydratase domain containing 2
EGR1 early growth response 1
ENO2 enolase 2 (gamma, neuronal)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
EZR ezrin
FAM149A family with sequence similarity 149, member A
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
FOLR1 folate receptor 1 (adult)
GDI1 GDP dissociation inhibitor 1
GPM6A glycoprotein M6A
GPNMB glycoprotein (transmembrane) nmb
GPX3 glutathione peroxidase 3
GSTP1 glutathione S-transferase pi 1
GUSBP3 glucuronidase, beta pseudogene 3
HBE1 hemoglobin, epsilon 1
HIST1H1C histone cluster 1, H1c
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HMGN5 high mobility group nucleosome binding domain 5
HP haptoglobin
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP7 insulin-like growth factor binding protein 7
ISG15 ISG15 ubiquitin-like modifier
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LAMP3 lysosomal-associated membrane protein 3
LAPTM4B lysosomal protein transmembrane 4 beta
LAPTM5 lysosomal protein transmembrane 5
LDHB lactate dehydrogenase B
LDOC1 leucine zipper, down-regulated in cancer 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LOC100272216 uncharacterized LOC100272216
LOC100505650 uncharacterized LOC100505650
LRRC17 leucine rich repeat containing 17
LTA4H leukotriene A4 hydrolase
LYN LYN proto-oncogene, Src family tyrosine kinase
MAN1A1 mannosidase, alpha, class 1A, member 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MEIS2 Meis homeobox 2
METRN meteorin, glial cell differentiation regulator
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
MPP1 membrane protein, palmitoylated 1, 55kDa
MX1 MX dynamin-like GTPase 1
MXRA7 matrix-remodelling associated 7
NPIPB3 nuclear pore complex interacting protein family, member B3
NQO2 NAD(P)H dehydrogenase, quinone 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUCB1 nucleobindin 1
OSBPL10 oxysterol binding protein-like 10
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PGAM1 phosphoglycerate mutase 1 (brain)
PLAT plasminogen activator, tissue
PLBD1 phospholipase B domain containing 1
PLVAP plasmalemma vesicle associated protein
PRKCQ protein kinase C, theta
PRSS21 protease, serine, 21 (testisin)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
RAP2C RAP2C, member of RAS oncogene family
RBP1 retinol binding protein 1, cellular
RGCC regulator of cell cycle
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPL10 ribosomal protein L10
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCGB1D2 secretoglobin, family 1D, member 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFRP4 secreted frizzled-related protein 4
SFTPB surfactant protein B
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SNX10 sorting nexin 10
SPARCL1 SPARC-like 1 (hevin)
SPON1 spondin 1, extracellular matrix protein
STC1 stanniocalcin 1
TARBP1 TAR (HIV-1) RNA binding protein 1
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TCL1A T-cell leukemia/lymphoma 1A
THY1 Thy-1 cell surface antigen
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPM4 tropomyosin 4
TPP1 tripeptidyl peptidase I
TRA2A transformer 2 alpha homolog (Drosophila)
TRIB2 tribbles pseudokinase 2
TSPAN12 tetraspanin 12
TYROBP TYRO protein tyrosine kinase binding protein
VAMP7 vesicle-associated membrane protein 7
VEGFA vascular endothelial growth factor A
WFDC2 WAP four-disulfide core domain 2
WSB1 WD repeat and SOCS box containing 1
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADRA2A adrenoceptor alpha 2A
AHNAK AHNAK nucleoprotein
AKAP1 A kinase (PRKA) anchor protein 1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ASCC3 activating signal cointegrator 1 complex subunit 3
ATF5 activating transcription factor 5
ATMIN ATM interactor
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
B3GNT1
BAG3 BCL2-associated athanogene 3
C14ORF169 chromosome 14 open reading frame 169
C1ORF116 chromosome 1 open reading frame 116
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCNA2 cyclin A2
CCNG2 cyclin G2
CD164 CD164 molecule, sialomucin
CDC123 cell division cycle 123
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL5 chemokine (C-X-C motif) ligand 5
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLK1 delta-like 1 homolog (Drosophila)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUOX2 dual oxidase 2
DUSP7 dual specificity phosphatase 7
FCGBP Fc fragment of IgG binding protein
FOXO3 forkhead box O3
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GCH1 GTP cyclohydrolase 1
GLOD4 glyoxalase domain containing 4
GPATCH8 G patch domain containing 8
GRB10 growth factor receptor-bound protein 10
HOXC6 homeobox C6
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
INHBB inhibin, beta B
KIF20A kinesin family member 20A
KRT15 keratin 15, type I
KRT17 keratin 17, type I
KRT7 keratin 7, type II
LBR lamin B receptor
MB myoglobin
MED1 mediator complex subunit 1
MOB4 MOB family member 4, phocein
MPZL1 myelin protein zero-like 1
MYBPC1 myosin binding protein C, slow type
NET1 neuroepithelial cell transforming 1
NFIB nuclear factor I/B
NGDN neuroguidin, EIF4E binding protein
NKX3-1 NK3 homeobox 1
NRN1 neuritin 1
NUP62 nucleoporin 62kDa
NUP98 nucleoporin 98kDa
PCNA proliferating cell nuclear antigen
PDZRN3 PDZ domain containing ring finger 3
PEG3 paternally expressed 3
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PIP prolactin-induced protein
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLAC8 placenta-specific 8
PLCB4 phospholipase C, beta 4
PLK1 polo-like kinase 1
PNP purine nucleoside phosphorylase
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRPF4B pre-mRNA processing factor 4B
PSCA prostate stem cell antigen
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
RAB14 RAB14, member RAS oncogene family
RAE1 ribonucleic acid export 1
RANBP2 RAN binding protein 2
RFK riboflavin kinase
RNMT RNA (guanine-7-) methyltransferase
RNPS1 RNA binding protein S1, serine-rich domain
RPL39L ribosomal protein L39-like
SCAND1 SCAN domain containing 1
SEC24B SEC24 family member B
SEH1L SEH1-like (S. cerevisiae)
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SNAP25 synaptosomal-associated protein, 25kDa
SOX4 SRY (sex determining region Y)-box 4
STMN2 stathmin 2
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TBP TATA box binding protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFAM transcription factor A, mitochondrial
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFB2M transcription factor B2, mitochondrial
TFF1 trefoil factor 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM4SF1 transmembrane 4 L six family member 1
TMEM70 transmembrane protein 70
TMEM97 transmembrane protein 97
TMX4 thioredoxin-related transmembrane protein 4
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TOB1 transducer of ERBB2, 1
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TRIM29 tripartite motif containing 29
TSPYL1 TSPY-like 1
TXLNA taxilin alpha
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2C ubiquitin-conjugating enzyme E2C
USP22 ubiquitin specific peptidase 22
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VGLL4 vestigial-like family member 4
WDR82 WD repeat domain 82
WTAP Wilms tumor 1 associated protein
XBP1 X-box binding protein 1
ZNF217 zinc finger protein 217