BRD-K13390322_AT-7519_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K13390322_AT-7519_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
CALD1 caldesmon 1
CCL20 chemokine (C-C motif) ligand 20
CHI3L2 chitinase 3-like 2
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL5A2 collagen, type V, alpha 2
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
CSTA cystatin A (stefin A)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
DCN decorin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FXYD2 FXYD domain containing ion transport regulator 2
GJA1 gap junction protein, alpha 1, 43kDa
GPX1 glutathione peroxidase 1
HBB hemoglobin, beta
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KIAA0226L KIAA0226-like
LAPTM4B lysosomal protein transmembrane 4 beta
LCN2 lipocalin 2
MAN1A1 mannosidase, alpha, class 1A, member 1
NID2 nidogen 2 (osteonidogen)
NREP neuronal regeneration related protein
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
ORM1 orosomucoid 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PF4 platelet factor 4
PIP prolactin-induced protein
PLAC8 placenta-specific 8
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PYCARD PYD and CARD domain containing
RAB4A RAB4A, member RAS oncogene family
SDC2 syndecan 2
SPON2 spondin 2, extracellular matrix protein
TMEM158 transmembrane protein 158 (gene/pseudogene)
TUBA1A tubulin, alpha 1a
UGP2 UDP-glucose pyrophosphorylase 2

decreased expression

Symbol Name
AHR aryl hydrocarbon receptor
APOLD1 apolipoprotein L domain containing 1
AQP1 aquaporin 1 (Colton blood group)
BAMBI BMP and activin membrane-bound inhibitor
BTG2 BTG family, member 2
CDC25A cell division cycle 25A
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CYR61 cysteine-rich, angiogenic inducer, 61
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EDNRB endothelin receptor type B
EGR2 early growth response 2
F3 coagulation factor III (thromboplastin, tissue factor)
FABP7 fatty acid binding protein 7, brain
FGF13 fibroblast growth factor 13
FOSL1 FOS-like antigen 1
GADD45B growth arrest and DNA-damage-inducible, beta
GATA6 GATA binding protein 6
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBEGF heparin-binding EGF-like growth factor
HES1 hes family bHLH transcription factor 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV3-19 immunoglobulin lambda variable 3-19
KRT81 keratin 81, type II
LIMCH1 LIM and calponin homology domains 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LPCAT1 lysophosphatidylcholine acyltransferase 1
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
NOV nephroblastoma overexpressed
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
PCP4 Purkinje cell protein 4
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
SAP30 Sin3A-associated protein, 30kDa
TP53BP2 tumor protein p53 binding protein 2
TSC22D2 TSC22 domain family, member 2