BRD-K13390322_AT-7519_BT20_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

299 genes differentially expressed following the BRD-K13390322_AT-7519_BT20_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ABAT 4-aminobutyrate aminotransferase
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACBD3 acyl-CoA binding domain containing 3
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AIF1 allograft inflammatory factor 1
AKAP8 A kinase (PRKA) anchor protein 8
AKAP8L A kinase (PRKA) anchor protein 8-like
ALB albumin
AMPH amphiphysin
APOC2 apolipoprotein C-II
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPN asporin
BAG4 BCL2-associated athanogene 4
BEX1 brain expressed, X-linked 1
BHLHE40 basic helix-loop-helix family, member e40
BRD2 bromodomain containing 2
BTG3 BTG family, member 3
C3 complement component 3
CALD1 caldesmon 1
CCL20 chemokine (C-C motif) ligand 20
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD99 CD99 molecule
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CFB complement factor B
CHERP calcium homeostasis endoplasmic reticulum protein
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLP1 cleavage and polyadenylation factor I subunit 1
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
COQ10B coenzyme Q10 homolog B (S. cerevisiae)
CPE carboxypeptidase E
CSTA cystatin A (stefin A)
CTSB cathepsin B
CTSG cathepsin G
CTTN cortactin
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DEFA4 defensin, alpha 4, corticostatin
DEFB1 defensin, beta 1
DERL1 derlin 1
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DPT dermatopontin
DUSP10 dual specificity phosphatase 10
DUSP2 dual specificity phosphatase 2
ECHDC2 enoyl CoA hydratase domain containing 2
ECM1 extracellular matrix protein 1
EGR1 early growth response 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EREG epiregulin
ESR1 estrogen receptor 1
ETF1 eukaryotic translation termination factor 1
FAM46A family with sequence similarity 46, member A
FASTKD5 FAST kinase domains 5
FEM1B fem-1 homolog b (C. elegans)
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
FRS2 fibroblast growth factor receptor substrate 2
FRZB frizzled-related protein
FUCA1 fucosidase, alpha-L- 1, tissue
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLC glutamate-cysteine ligase, catalytic subunit
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GLUL glutamate-ammonia ligase
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPC3 glypican 3
GPNMB glycoprotein (transmembrane) nmb
GPX3 glutathione peroxidase 3
GTF2B general transcription factor IIB
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLF hepatic leukemia factor
HMGN5 high mobility group nucleosome binding domain 5
HMOX1 heme oxygenase 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGFBP3 insulin-like growth factor binding protein 3
IL6R interleukin 6 receptor
IRX5 iroquois homeobox 5
ITM2A integral membrane protein 2A
JAG1 jagged 1
JMJD6 jumonji domain containing 6
KLF10 Kruppel-like factor 10
LAMP1 lysosomal-associated membrane protein 1
LYN LYN proto-oncogene, Src family tyrosine kinase
LYZ lysozyme
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MATN2 matrilin 2
MBP myelin basic protein
MED6 mediator complex subunit 6
MMP10 matrix metallopeptidase 10
MMP9 matrix metallopeptidase 9
MOAP1 modulator of apoptosis 1
MXRA7 matrix-remodelling associated 7
NACA nascent polypeptide-associated complex alpha subunit
NAP1L2 nucleosome assembly protein 1-like 2
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NECAP1 NECAP endocytosis associated 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
NUPL1 nucleoporin like 1
OAT ornithine aminotransferase
OLFM1 olfactomedin 1
ORM1 orosomucoid 1
PALLD palladin, cytoskeletal associated protein
PEG3 paternally expressed 3
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLTP phospholipid transfer protein
PPIF peptidylprolyl isomerase F
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKCB protein kinase C, beta
PRNP prion protein
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PTN pleiotrophin
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RNASE4 ribonuclease, RNase A family, 4
RNF139 ring finger protein 139
RNMT RNA (guanine-7-) methyltransferase
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS21 ribosomal protein S21
S100A2 S100 calcium binding protein A2
SCG5 secretogranin V
SCGB2A1 secretoglobin, family 2A, member 1
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SMAD7 SMAD family member 7
SMNDC1 survival motor neuron domain containing 1
SON SON DNA binding protein
SPARCL1 SPARC-like 1 (hevin)
SPEN spen family transcriptional repressor
STK17A serine/threonine kinase 17a
STK17B serine/threonine kinase 17b
STXBP6 syntaxin binding protein 6 (amisyn)
SYBU syntabulin (syntaxin-interacting)
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TERF2IP telomeric repeat binding factor 2, interacting protein
TESC tescalcin
TFB2M transcription factor B2, mitochondrial
TFF3 trefoil factor 3 (intestinal)
TICAM1 toll-like receptor adaptor molecule 1
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM70 transmembrane protein 70
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TRIO trio Rho guanine nucleotide exchange factor
TSPAN7 tetraspanin 7
USP36 ubiquitin specific peptidase 36
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZBTB10 zinc finger and BTB domain containing 10
ZC3H15 zinc finger CCCH-type containing 15
ZCCHC2 zinc finger, CCHC domain containing 2
ZFX zinc finger protein, X-linked
ZMYM5 zinc finger, MYM-type 5
ZNF134 zinc finger protein 134
ZNF267 zinc finger protein 267
ZNF394 zinc finger protein 394

decreased expression

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADGRG6 adhesion G protein-coupled receptor G6
AIM1 absent in melanoma 1
ALCAM activated leukocyte cell adhesion molecule
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA4 annexin A4
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ASCC3 activating signal cointegrator 1 complex subunit 3
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATF5 activating transcription factor 5
ATP10D ATPase, class V, type 10D
AURKA aurora kinase A
BASP1 brain abundant, membrane attached signal protein 1
BRD3 bromodomain containing 3
CAV2 caveolin 2
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDK19 cyclin-dependent kinase 19
CDKN3 cyclin-dependent kinase inhibitor 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CEP55 centrosomal protein 55kDa
CKS2 CDC28 protein kinase regulatory subunit 2
CLIC3 chloride intracellular channel 3
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COG4 component of oligomeric golgi complex 4
COMMD3 COMM domain containing 3
COTL1 coactosin-like F-actin binding protein 1
CTBP2 C-terminal binding protein 2
DAPK1 death-associated protein kinase 1
DDIT4 DNA-damage-inducible transcript 4
DERA deoxyribose-phosphate aldolase (putative)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DPYSL2 dihydropyrimidinase-like 2
DYNLT1 dynein, light chain, Tctex-type 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFHD1 EF-hand domain family, member D1
ELF5 E74-like factor 5 (ets domain transcription factor)
ERBB2 erb-b2 receptor tyrosine kinase 2
FAR2 fatty acyl CoA reductase 2
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FOXD1 forkhead box D1
FZD7 frizzled class receptor 7
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPRC5A G protein-coupled receptor, class C, group 5, member A
HMG20B high mobility group 20B
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOXB7 homeobox B7
HOXC10 homeobox C10
HOXC6 homeobox C6
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP5 insulin-like growth factor binding protein 5
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGSF3 immunoglobulin superfamily, member 3
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
JADE2 jade family PHD finger 2
KAZN kazrin, periplakin interacting protein
KIAA1033 KIAA1033
KIF20A kinesin family member 20A
KLF4 Kruppel-like factor 4 (gut)
KRT18 keratin 18, type I
LASP1 LIM and SH3 protein 1
LINC00341 long intergenic non-protein coding RNA 341
LXN latexin
MACF1 microtubule-actin crosslinking factor 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7 microtubule-associated protein 7
MBNL2 muscleblind-like splicing regulator 2
MGP matrix Gla protein
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYOF myoferlin
NAGK N-acetylglucosamine kinase
NAV2 neuron navigator 2
NDC80 NDC80 kinetochore complex component
NEK2 NIMA-related kinase 2
NMI N-myc (and STAT) interactor
NNMT nicotinamide N-methyltransferase
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUSAP1 nucleolar and spindle associated protein 1
OPN3 opsin 3
PADI2 peptidyl arginine deiminase, type II
PDS5A PDS5 cohesin associated factor A
PLA2G16 phospholipase A2, group XVI
PON2 paraoxonase 2
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PSIP1 PC4 and SFRS1 interacting protein 1
PXDN peroxidasin
RAB31 RAB31, member RAS oncogene family
RACGAP1 Rac GTPase activating protein 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A11 S100 calcium binding protein A11
S100A7 S100 calcium binding protein A7
SH3BP4 SH3-domain binding protein 4
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SMAGP small cell adhesion glycoprotein
SMC4 structural maintenance of chromosomes 4
STX7 syntaxin 7
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TBL1X transducin (beta)-like 1X-linked
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TDRD12 tudor domain containing 12
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP53I3 tumor protein p53 inducible protein 3
TPD52L1 tumor protein D52-like 1
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TRIM2 tripartite motif containing 2
TRIOBP TRIO and F-actin binding protein
TRIP6 thyroid hormone receptor interactor 6
TST thiosulfate sulfurtransferase (rhodanese)
TUBB6 tubulin, beta 6 class V
VIM vimentin
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
ZIC1 Zic family member 1
ZNF185 zinc finger protein 185 (LIM domain)
ZNF638 zinc finger protein 638