BRD-K12906962_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

86 genes differentially expressed following the BRD-K12906962_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGTR1 angiotensin II receptor, type 1
APOC1 apolipoprotein C-I
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CLU clusterin
COL1A1 collagen, type I, alpha 1
CRABP2 cellular retinoic acid binding protein 2
CRISP3 cysteine-rich secretory protein 3
DDIT4 DNA-damage-inducible transcript 4
FOXO4 forkhead box O4
GLUL glutamate-ammonia ligase
GPER1 G protein-coupled estrogen receptor 1
GPM6A glycoprotein M6A
GRAMD3 GRAM domain containing 3
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOPX HOP homeobox
KLHL24 kelch-like family member 24
LAMP2 lysosomal-associated membrane protein 2
MEIS1 Meis homeobox 1
MXI1 MAX interactor 1, dimerization protein
MYO10 myosin X
OXTR oxytocin receptor
PBX1 pre-B-cell leukemia homeobox 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLAC8 placenta-specific 8
QPRT quinolinate phosphoribosyltransferase
RAB31 RAB31, member RAS oncogene family
RRAGD Ras-related GTP binding D
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SESN1 sestrin 1
SLAMF7 SLAM family member 7
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SORBS3 sorbin and SH3 domain containing 3
STOM stomatin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THY1 Thy-1 cell surface antigen
TXNL4B thioredoxin-like 4B

decreased expression

Symbol Name
AIM1 absent in melanoma 1
CD24 CD24 molecule
CD9 CD9 molecule
COCH cochlin
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FLRT3 fibronectin leucine rich transmembrane protein 3
GLIPR1 GLI pathogenesis-related 1
HSPA1A heat shock 70kDa protein 1A
IER3 immediate early response 3
IGFBP7 insulin-like growth factor binding protein 7
KCTD12 potassium channel tetramerization domain containing 12
KLF4 Kruppel-like factor 4 (gut)
LUM lumican
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MFSD10 major facilitator superfamily domain containing 10
NDNF neuron-derived neurotrophic factor
NKX3-1 NK3 homeobox 1
NREP neuronal regeneration related protein
PHLDA2 pleckstrin homology-like domain, family A, member 2
POSTN periostin, osteoblast specific factor
PRNP prion protein
PRR7 proline rich 7 (synaptic)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RNH1 ribonuclease/angiogenin inhibitor 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFN stratifin
SIK1 salt-inducible kinase 1
SOX4 SRY (sex determining region Y)-box 4
SPRY2 sprouty homolog 2 (Drosophila)
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK39 serine threonine kinase 39
STX1A syntaxin 1A (brain)
SVIL supervillin
TACSTD2 tumor-associated calcium signal transducer 2
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TFPI2 tissue factor pathway inhibitor 2
TOR1A torsin family 1, member A (torsin A)
TPSAB1 tryptase alpha/beta 1
TSPAN13 tetraspanin 13
VEGFA vascular endothelial growth factor A