BRD-K12787259_CX-5461_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

98 genes differentially expressed following the BRD-K12787259_CX-5461_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACBD3 acyl-CoA binding domain containing 3
AKR1C3 aldo-keto reductase family 1, member C3
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATP10B ATPase, class V, type 10B
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATPIF1 ATPase inhibitory factor 1
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHMP4A charged multivesicular body protein 4A
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CIRBP cold inducible RNA binding protein
COL9A2 collagen, type IX, alpha 2
CTSS cathepsin S
DDB2 damage-specific DNA binding protein 2, 48kDa
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EIF5A eukaryotic translation initiation factor 5A
FKBP1B FK506 binding protein 1B, 12.6 kDa
GALC galactosylceramidase
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
GPX3 glutathione peroxidase 3
GSDMB gasdermin B
GSTM3 glutathione S-transferase mu 3 (brain)
HDAC1 histone deacetylase 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HLA-C major histocompatibility complex, class I, C
HSPB1 heat shock 27kDa protein 1
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
ISG15 ISG15 ubiquitin-like modifier
MAN1A1 mannosidase, alpha, class 1A, member 1
MINK1 misshapen-like kinase 1
MT1F metallothionein 1F
MX1 MX dynamin-like GTPase 1
OASL 2'-5'-oligoadenylate synthetase-like
PDE4C phosphodiesterase 4C, cAMP-specific
RNF167 ring finger protein 167
RPS27L ribosomal protein S27-like
SLC35E1 solute carrier family 35, member E1
TXNIP thioredoxin interacting protein
UROD uroporphyrinogen decarboxylase
ZIC1 Zic family member 1
ZNF160 zinc finger protein 160

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
AIM1 absent in melanoma 1
ANK2 ankyrin 2, neuronal
APOD apolipoprotein D
AUTS2 autism susceptibility candidate 2
C7 complement component 7
CCL19 chemokine (C-C motif) ligand 19
CD93 CD93 molecule
CENPE centromere protein E, 312kDa
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL9 chemokine (C-X-C motif) ligand 9
CYB5A cytochrome b5 type A (microsomal)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FASN fatty acid synthase
FKBP5 FK506 binding protein 5
FLRT2 fibronectin leucine rich transmembrane protein 2
GATA3 GATA binding protein 3
GPM6B glycoprotein M6B
GRWD1 glutamate-rich WD repeat containing 1
HIST1H2BK histone cluster 1, H2bk
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
LTF lactotransferrin
MGP matrix Gla protein
MMP9 matrix metallopeptidase 9
MPZL2 myelin protein zero-like 2
MSMO1 methylsterol monooxygenase 1
MTUS1 microtubule associated tumor suppressor 1
MYH11 myosin, heavy chain 11, smooth muscle
NR2F2 nuclear receptor subfamily 2, group F, member 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PPL periplakin
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP1 secreted frizzled-related protein 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLIT2 slit homolog 2 (Drosophila)
SQLE squalene epoxidase
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SYBU syntabulin (syntaxin-interacting)
TAGLN transgelin