BRD-K12787259_CX-5461_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

71 genes differentially expressed following the BRD-K12787259_CX-5461_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARHGAP29 Rho GTPase activating protein 29
ATF5 activating transcription factor 5
CCND1 cyclin D1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
COCH cochlin
CRIP1 cysteine-rich protein 1 (intestinal)
DACH1 dachshund family transcription factor 1
DSP desmoplakin
EPCAM epithelial cell adhesion molecule
FKBP5 FK506 binding protein 5
GPER1 G protein-coupled estrogen receptor 1
GPX7 glutathione peroxidase 7
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
LIMS1 LIM and senescent cell antigen-like domains 1
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MFAP5 microfibrillar associated protein 5
MKNK2 MAP kinase interacting serine/threonine kinase 2
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAX8 paired box 8
PCP4 Purkinje cell protein 4
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC38A1 solute carrier family 38, member 1
SOX11 SRY (sex determining region Y)-box 11
TMEM176B transmembrane protein 176B
TUBB2B tubulin, beta 2B class IIb
TXNDC9 thioredoxin domain containing 9
TXNIP thioredoxin interacting protein
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VNN1 vanin 1

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ASNS asparagine synthetase (glutamine-hydrolyzing)
BCAP31 B-cell receptor-associated protein 31
CCND2 cyclin D2
COPS7A COP9 signalosome subunit 7A
CPA3 carboxypeptidase A3 (mast cell)
CRABP2 cellular retinoic acid binding protein 2
CXCL5 chemokine (C-X-C motif) ligand 5
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FKBP1A FK506 binding protein 1A, 12kDa
FOXF1 forkhead box F1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GLUL glutamate-ammonia ligase
HHEX hematopoietically expressed homeobox
LMO4 LIM domain only 4
PDE4B phosphodiesterase 4B, cAMP-specific
PLK2 polo-like kinase 2
PMP22 peripheral myelin protein 22
PTPRE protein tyrosine phosphatase, receptor type, E
RBPMS RNA binding protein with multiple splicing
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPS4Y1 ribosomal protein S4, Y-linked 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SFRP1 secreted frizzled-related protein 1
SIK1 salt-inducible kinase 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC39A14 solute carrier family 39 (zinc transporter), member 14
TGFB1 transforming growth factor, beta 1
TPM4 tropomyosin 4
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIB2 tribbles pseudokinase 2
YBX3 Y box binding protein 3