BRD-K12502280_TG-101348_SKBR3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K12502280_TG-101348_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
APOD apolipoprotein D
AQP3 aquaporin 3 (Gill blood group)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK1 death-associated protein kinase 1
DDIT4 DNA-damage-inducible transcript 4
ENO2 enolase 2 (gamma, neuronal)
FNDC3B fibronectin type III domain containing 3B
FOLR1 folate receptor 1 (adult)
H1F0 H1 histone family, member 0
HACD1 3-hydroxyacyl-CoA dehydratase 1
HIST1H2AC histone cluster 1, H2ac
HIST2H2BE histone cluster 2, H2be
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFITM1 interferon induced transmembrane protein 1
ITGAV integrin, alpha V
KIAA0226L KIAA0226-like
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MTSS1 metastasis suppressor 1
NCAM1 neural cell adhesion molecule 1
NRGN neurogranin (protein kinase C substrate, RC3)
NRIP1 nuclear receptor interacting protein 1
PHGDH phosphoglycerate dehydrogenase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PSAT1 phosphoserine aminotransferase 1
PYGL phosphorylase, glycogen, liver
RHOBTB3 Rho-related BTB domain containing 3
SSFA2 sperm specific antigen 2
STXBP1 syntaxin binding protein 1
SYBU syntabulin (syntaxin-interacting)
TGFBI transforming growth factor, beta-induced, 68kDa
TMSB15A thymosin beta 15a
TSPAN3 tetraspanin 3
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
BHLHE41 basic helix-loop-helix family, member e41
C2CD5 C2 calcium-dependent domain containing 5
C7 complement component 7
CCL2 chemokine (C-C motif) ligand 2
CDC25A cell division cycle 25A
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK4 cyclin-dependent kinase 4
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COL10A1 collagen, type X, alpha 1
CXCR4 chemokine (C-X-C motif) receptor 4
DCN decorin
FABP4 fatty acid binding protein 4, adipocyte
FAS Fas cell surface death receptor
GBP2 guanylate binding protein 2, interferon-inducible
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
KCTD12 potassium channel tetramerization domain containing 12
KRT19 keratin 19, type I
KRT7 keratin 7, type II
MAGEA3 melanoma antigen family A3
MCTP1 multiple C2 domains, transmembrane 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLAC8 placenta-specific 8
RGS5 regulator of G-protein signaling 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SORBS3 sorbin and SH3 domain containing 3
SOX4 SRY (sex determining region Y)-box 4
SPINK1 serine peptidase inhibitor, Kazal type 1
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFF1 trefoil factor 1
TLR4 toll-like receptor 4
TMEM97 transmembrane protein 97
TSPAN8 tetraspanin 8
VCAM1 vascular cell adhesion molecule 1