BRD-K12502280_TG-101348_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

143 genes differentially expressed following the BRD-K12502280_TG-101348_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ASPN asporin
ASS1 argininosuccinate synthase 1
C14ORF132 chromosome 14 open reading frame 132
CALCA calcitonin-related polypeptide alpha
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDO1 cysteine dioxygenase type 1
CES2 carboxylesterase 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL3A1 collagen, type III, alpha 1
CREG1 cellular repressor of E1A-stimulated genes 1
CTSH cathepsin H
CTSK cathepsin K
DUOX2 dual oxidase 2
EDNRA endothelin receptor type A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FAM134B family with sequence similarity 134, member B
FBLN1 fibulin 1
FBN2 fibrillin 2
GPNMB glycoprotein (transmembrane) nmb
GSDMB gasdermin B
HIST1H1C histone cluster 1, H1c
IRS2 insulin receptor substrate 2
LIMCH1 LIM and calponin homology domains 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN1C1 mannosidase, alpha, class 1C, member 1
MOXD1 monooxygenase, DBH-like 1
NELL2 NEL-like 2 (chicken)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
NTS neurotensin
NUPR1 nuclear protein, transcriptional regulator, 1
NVL nuclear VCP-like
PCDH9 protocadherin 9
PER3 period circadian clock 3
PHYH phytanoyl-CoA 2-hydroxylase
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PPL periplakin
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAB31 RAB31, member RAS oncogene family
SATB1 SATB homeobox 1
SCPEP1 serine carboxypeptidase 1
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SOBP sine oculis binding protein homolog (Drosophila)
SQSTM1 sequestosome 1
STXBP1 syntaxin binding protein 1
TENM1 teneurin transmembrane protein 1
TFF1 trefoil factor 1
TPD52L1 tumor protein D52-like 1
TRAPPC6A trafficking protein particle complex 6A

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
AK4 adenylate kinase 4
AMIGO2 adhesion molecule with Ig-like domain 2
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
APOD apolipoprotein D
AREG amphiregulin
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BCL2A1 BCL2-related protein A1
BIRC3 baculoviral IAP repeat containing 3
CAV1 caveolin 1, caveolae protein, 22kDa
CBR3 carbonyl reductase 3
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CD200 CD200 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CLIC3 chloride intracellular channel 3
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRIP2 cysteine-rich protein 2
CRYZ crystallin, zeta (quinone reductase)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
EDN1 endothelin 1
EGF epidermal growth factor
ERAP2 endoplasmic reticulum aminopeptidase 2
FABP7 fatty acid binding protein 7, brain
FKBP14 FK506 binding protein 14, 22 kDa
FOSL1 FOS-like antigen 1
FZD6 frizzled class receptor 6
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GBP1 guanylate binding protein 1, interferon-inducible
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GLIPR1 GLI pathogenesis-related 1
GLS glutaminase
HAPLN1 hyaluronan and proteoglycan link protein 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ICAM1 intercellular adhesion molecule 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
IL32 interleukin 32
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
LAMC2 laminin, gamma 2
LDLR low density lipoprotein receptor
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK13 mitogen-activated protein kinase 13
MGLL monoglyceride lipase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MOK MOK protein kinase
MSMO1 methylsterol monooxygenase 1
MUC16 mucin 16, cell surface associated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NT5E 5'-nucleotidase, ecto (CD73)
OXTR oxytocin receptor
PDGFA platelet-derived growth factor alpha polypeptide
PDGFC platelet derived growth factor C
PLAT plasminogen activator, tissue
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNO1 partner of NOB1 homolog (S. cerevisiae)
PON2 paraoxonase 2
PRSS23 protease, serine, 23
PTX3 pentraxin 3, long
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH3GLB1 SH3-domain GRB2-like endophilin B1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC35F2 solute carrier family 35, member F2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SQLE squalene epoxidase
STK10 serine/threonine kinase 10
STK17A serine/threonine kinase 17a
SUB1 SUB1 homolog (S. cerevisiae)
TM4SF1 transmembrane 4 L six family member 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNIP1 TNFAIP3 interacting protein 1
TPM1 tropomyosin 1 (alpha)
TXNDC9 thioredoxin domain containing 9
UGCG UDP-glucose ceramide glucosyltransferase
UGDH UDP-glucose 6-dehydrogenase
XIST X inactive specific transcript (non-protein coding)