BRD-K12502280_TG-101348_BT20_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K12502280_TG-101348_BT20_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
AMDHD2 amidohydrolase domain containing 2
ANXA6 annexin A6
ARG2 arginase 2
CREG1 cellular repressor of E1A-stimulated genes 1
CTSH cathepsin H
DAPK1 death-associated protein kinase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSP desmoplakin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HIST2H2BE histone cluster 2, H2be
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IPW imprinted in Prader-Willi syndrome (non-protein coding)
MATN2 matrilin 2
NKX3-1 NK3 homeobox 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
SEPP1 selenoprotein P, plasma, 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
STXBP1 syntaxin binding protein 1
TESC tescalcin

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AHNAK2 AHNAK nucleoprotein 2
ANXA1 annexin A1
CA2 carbonic anhydrase II
CAPN1 calpain 1, (mu/I) large subunit
CTSC cathepsin C
EGFR epidermal growth factor receptor
G0S2 G0/G1 switch 2
GBP1 guanylate binding protein 1, interferon-inducible
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPX3 glutathione peroxidase 3
HBB hemoglobin, beta
HMGA1 high mobility group AT-hook 1
HSPA2 heat shock 70kDa protein 2
LCN2 lipocalin 2
LXN latexin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MGLL monoglyceride lipase
NARFL nuclear prelamin A recognition factor-like
NT5E 5'-nucleotidase, ecto (CD73)
PLAC8 placenta-specific 8
PRSS23 protease, serine, 23
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SCGB2A1 secretoglobin, family 2A, member 1
SORBS1 sorbin and SH3 domain containing 1
SPON1 spondin 1, extracellular matrix protein
SPRY2 sprouty homolog 2 (Drosophila)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPBG trophoblast glycoprotein