BRD-K12040459_AT7867_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

22 genes differentially expressed following the BRD-K12040459_AT7867_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARID5B AT rich interactive domain 5B (MRF1-like)
CD24 CD24 molecule
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
FGR FGR proto-oncogene, Src family tyrosine kinase
GPC4 glypican 4
GSTT1 glutathione S-transferase theta 1
LTF lactotransferrin
NRIP1 nuclear receptor interacting protein 1
NTS neurotensin
PPAP2B phosphatidic acid phosphatase type 2B
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
CADM1 cell adhesion molecule 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
FABP1 fatty acid binding protein 1, liver
GADD45B growth arrest and DNA-damage-inducible, beta
LRRC17 leucine rich repeat containing 17
PDGFC platelet derived growth factor C
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
WT1 Wilms tumor 1