BRD-K11671649_5-amino-1-ethyl-3-(naphthalen-1-ylmethyl)-1H-pyrazole-4-carbonitrile CAL-NCGC-061_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

60 genes differentially expressed following the BRD-K11671649_5-amino-1-ethyl-3-(naphthalen-1-ylmethyl)-1H-pyrazole-4-carbonitrile CAL-NCGC-061_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
COCH cochlin
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DACH1 dachshund family transcription factor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DSG2 desmoglein 2
EFNB2 ephrin-B2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FXYD3 FXYD domain containing ion transport regulator 3
GATA2 GATA binding protein 2
GPX2 glutathione peroxidase 2
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
KLF5 Kruppel-like factor 5 (intestinal)
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
NDRG1 N-myc downstream regulated 1
OLFM4 olfactomedin 4
PDGFC platelet derived growth factor C
PRDX2 peroxiredoxin 2
PRKCB protein kinase C, beta
RBKS ribokinase
RPS4Y1 ribosomal protein S4, Y-linked 1
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STK26 serine/threonine protein kinase 26
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNC tenascin C
TPSB2 tryptase beta 2 (gene/pseudogene)
TSPAN8 tetraspanin 8
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ARL4C ADP-ribosylation factor-like 4C
ASCL1 achaete-scute family bHLH transcription factor 1
BCL6 B-cell CLL/lymphoma 6
CD59 CD59 molecule, complement regulatory protein
CDC42 cell division cycle 42
CDKN2A cyclin-dependent kinase inhibitor 2A
CLIC3 chloride intracellular channel 3
CNPY3 canopy FGF signaling regulator 3
EFHD1 EF-hand domain family, member D1
EMP1 epithelial membrane protein 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM129A family with sequence similarity 129, member A
FKBP5 FK506 binding protein 5
GJA1 gap junction protein, alpha 1, 43kDa
HIST1H2BD histone cluster 1, H2bd
KLK10 kallikrein-related peptidase 10
KRT7 keratin 7, type II
LDHB lactate dehydrogenase B
LMO3 LIM domain only 3 (rhombotin-like 2)
MYOF myoferlin
PEA15 phosphoprotein enriched in astrocytes 15
PSPH phosphoserine phosphatase
RGCC regulator of cell cycle
SH3TC1 SH3 domain and tetratricopeptide repeats 1
TNS1 tensin 1
TUBB2A tubulin, beta 2A class IIa
XIST X inactive specific transcript (non-protein coding)