BRD-K11640013_Sulfamethazine sodium salt_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K11640013_Sulfamethazine sodium salt_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
ALOX5 arachidonate 5-lipoxygenase
AUTS2 autism susceptibility candidate 2
BCL2A1 BCL2-related protein A1
C9ORF16 chromosome 9 open reading frame 16
CADM1 cell adhesion molecule 1
CCL20 chemokine (C-C motif) ligand 20
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC5A C-type lectin domain family 5, member A
COL1A2 collagen, type I, alpha 2
COL6A3 collagen, type VI, alpha 3
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
DUSP1 dual specificity phosphatase 1
EIF1 eukaryotic translation initiation factor 1
ENO1 enolase 1, (alpha)
FMOD fibromodulin
ICAM1 intercellular adhesion molecule 1
IFI16 interferon, gamma-inducible protein 16
IL1R1 interleukin 1 receptor, type I
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
JUND jun D proto-oncogene
LASP1 LIM and SH3 protein 1
LEF1 lymphoid enhancer-binding factor 1
LY6E lymphocyte antigen 6 complex, locus E
MAOA monoamine oxidase A
MCL1 myeloid cell leukemia 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLAT plasminogen activator, tissue
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLSCR1 phospholipid scramblase 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RHOBTB3 Rho-related BTB domain containing 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC43A3 solute carrier family 43, member 3
SPRY2 sprouty homolog 2 (Drosophila)
TM4SF1 transmembrane 4 L six family member 1
TMEM259 transmembrane protein 259
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AFF1 AF4/FMR2 family, member 1
ARHGAP29 Rho GTPase activating protein 29
ARL4C ADP-ribosylation factor-like 4C
CALD1 caldesmon 1
CCL5 chemokine (C-C motif) ligand 5
CD8A CD8a molecule
CD96 CD96 molecule
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL9 chemokine (C-X-C motif) ligand 9
DEGS1 delta(4)-desaturase, sphingolipid 1
DLD dihydrolipoamide dehydrogenase
EFNB2 ephrin-B2
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMK granzyme K (granzyme 3; tryptase II)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
JCHAIN joining chain of multimeric IgA and IgM
KLHDC2 kelch domain containing 2
LAMB1 laminin, beta 1
LGMN legumain
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MALT1 MALT1 paracaspase
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
METRN meteorin, glial cell differentiation regulator
MTCL1 microtubule crosslinking factor 1
PDE4D phosphodiesterase 4D, cAMP-specific
PRF1 perforin 1 (pore forming protein)
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12)
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TES testin LIM domain protein
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRBC1 T cell receptor beta constant 1