BRD-K11267252_CH5424802_MCF7_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K11267252_CH5424802_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
AMIGO2 adhesion molecule with Ig-like domain 2
BCL3 B-cell CLL/lymphoma 3
C8ORF4 chromosome 8 open reading frame 4
CALB1 calbindin 1, 28kDa
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CKAP4 cytoskeleton-associated protein 4
CLIC3 chloride intracellular channel 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNTT DNA nucleotidylexotransferase
DOCK9 dedicator of cytokinesis 9
DUSP5 dual specificity phosphatase 5
E2F2 E2F transcription factor 2
GCH1 GTP cyclohydrolase 1
GDF15 growth differentiation factor 15
GLS glutaminase
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
KLK6 kallikrein-related peptidase 6
KRT13 keratin 13, type I
KRT23 keratin 23, type I
LUM lumican
LYZ lysozyme
MAL mal, T-cell differentiation protein
MAN1A1 mannosidase, alpha, class 1A, member 1
MSH6 mutS homolog 6
MYBPC1 myosin binding protein C, slow type
NPR3 natriuretic peptide receptor 3
P3H2 prolyl 3-hydroxylase 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PLIN2 perilipin 2
RHCG Rh family, C glycoprotein
SCN3A sodium channel, voltage gated, type III alpha subunit
SELL selectin L
SFRP1 secreted frizzled-related protein 1
TACSTD2 tumor-associated calcium signal transducer 2
TLE4 transducin-like enhancer of split 4
TNNT1 troponin T type 1 (skeletal, slow)
TRIM16 tripartite motif containing 16
TUFT1 tuftelin 1
WARS tryptophanyl-tRNA synthetase
XIST X inactive specific transcript (non-protein coding)
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
ASMTL acetylserotonin O-methyltransferase-like
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
CALR calreticulin
CAPN1 calpain 1, (mu/I) large subunit
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLEC2B C-type lectin domain family 2, member B
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
CP ceruloplasmin (ferroxidase)
FCGBP Fc fragment of IgG binding protein
FPGS folylpolyglutamate synthase
GPI glucose-6-phosphate isomerase
KCTD12 potassium channel tetramerization domain containing 12
LAMC2 laminin, gamma 2
MATN2 matrilin 2
MFSD10 major facilitator superfamily domain containing 10
MMP9 matrix metallopeptidase 9
MUC1 mucin 1, cell surface associated
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PRAF2 PRA1 domain family, member 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RPL39L ribosomal protein L39-like
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
TFPI2 tissue factor pathway inhibitor 2
TSPAN4 tetraspanin 4
TTC3 tetratricopeptide repeat domain 3
TTC39A tetratricopeptide repeat domain 39A