BRD-K11267252_CH5424802_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K11267252_CH5424802_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGR2 anterior gradient 2
AQP1 aquaporin 1 (Colton blood group)
BEX1 brain expressed, X-linked 1
BHLHE41 basic helix-loop-helix family, member e41
BMP4 bone morphogenetic protein 4
CASP7 caspase 7, apoptosis-related cysteine peptidase
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CES1 carboxylesterase 1
CFI complement factor I
CNN1 calponin 1, basic, smooth muscle
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
FHL1 four and a half LIM domains 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GBP1 guanylate binding protein 1, interferon-inducible
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IL6ST interleukin 6 signal transducer
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
LYZ lysozyme
MTUS1 microtubule associated tumor suppressor 1
MYH11 myosin, heavy chain 11, smooth muscle
MYLK myosin light chain kinase
NQO1 NAD(P)H dehydrogenase, quinone 1
OLFM4 olfactomedin 4
RHOBTB3 Rho-related BTB domain containing 3
SELENBP1 selenium binding protein 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SRGN serglycin
TAGLN transgelin
TARP TCR gamma alternate reading frame protein
TNS1 tensin 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARG1 arginase 1
BTG1 B-cell translocation gene 1, anti-proliferative
C1ORF116 chromosome 1 open reading frame 116
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CALML5 calmodulin-like 5
CDC20 cell division cycle 20
CKS2 CDC28 protein kinase regulatory subunit 2
CXCL12 chemokine (C-X-C motif) ligand 12
DSC1 desmocollin 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBXO11 F-box protein 11
GPATCH8 G patch domain containing 8
HAL histidine ammonia-lyase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
LCE2B late cornified envelope 2B
LOR loricrin
MAP7 microtubule-associated protein 7
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
TCL1A T-cell leukemia/lymphoma 1A
TPD52 tumor protein D52
TRPS1 trichorhinophalangeal syndrome I
VCAN versican
ZNF274 zinc finger protein 274
ZSCAN18 zinc finger and SCAN domain containing 18