BRD-K10882151_BO2 (inhibits RAD51)_PC3_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K10882151_BO2 (inhibits RAD51)_PC3_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EZR ezrin
H1F0 H1 histone family, member 0
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
JUN jun proto-oncogene
NQO1 NAD(P)H dehydrogenase, quinone 1
OLFML3 olfactomedin-like 3
PIR pirin (iron-binding nuclear protein)
PRKCB protein kinase C, beta
PROM1 prominin 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SST somatostatin
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ANXA1 annexin A1
ANXA3 annexin A3
ARHGAP29 Rho GTPase activating protein 29
CCNA2 cyclin A2
CCND2 cyclin D2
CFI complement factor I
CTSH cathepsin H
FXYD3 FXYD domain containing ion transport regulator 3
GPX1 glutathione peroxidase 1
HHEX hematopoietically expressed homeobox
HOXA10 homeobox A10
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IL1B interleukin 1, beta
IRS2 insulin receptor substrate 2
KRT15 keratin 15, type I
KRT7 keratin 7, type II
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MET MET proto-oncogene, receptor tyrosine kinase
NR2F2 nuclear receptor subfamily 2, group F, member 2
PDGFC platelet derived growth factor C
PIP prolactin-induced protein
PTGDS prostaglandin D2 synthase 21kDa (brain)
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TACSTD2 tumor-associated calcium signal transducer 2
TFRC transferrin receptor
THBS2 thrombospondin 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZIC1 Zic family member 1