BRD-K10882151_BO2 (inhibits RAD51)_HA1E_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-K10882151_BO2 (inhibits RAD51)_HA1E_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
BCL6 B-cell CLL/lymphoma 6
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CD52 CD52 molecule
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GPI glucose-6-phosphate isomerase
HK2 hexokinase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
INSIG1 insulin induced gene 1
KDM5D lysine (K)-specific demethylase 5D
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MUC4 mucin 4, cell surface associated
NEFL neurofilament, light polypeptide
NQO2 NAD(P)H dehydrogenase, quinone 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AHR aryl hydrocarbon receptor
BMI1 BMI1 proto-oncogene, polycomb ring finger
CAV1 caveolin 1, caveolae protein, 22kDa
CBR3 carbonyl reductase 3
CCL2 chemokine (C-C motif) ligand 2
CYR61 cysteine-rich, angiogenic inducer, 61
CYTH1 cytohesin 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
HOXA10 homeobox A10
HOXA5 homeobox A5
IER3 immediate early response 3
LAMP5 lysosomal-associated membrane protein family, member 5
LIMA1 LIM domain and actin binding 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PALLD palladin, cytoskeletal associated protein
PBX3 pre-B-cell leukemia homeobox 3
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RHOBTB3 Rho-related BTB domain containing 3
SDC2 syndecan 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SOX4 SRY (sex determining region Y)-box 4
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFRC transferrin receptor
XIST X inactive specific transcript (non-protein coding)