BRD-K10882151_BO2 (inhibits RAD51)_EFO27_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

131 genes differentially expressed following the BRD-K10882151_BO2 (inhibits RAD51)_EFO27_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
ALOX5 arachidonate 5-lipoxygenase
C10ORF10 chromosome 10 open reading frame 10
C2 complement component 2
C5AR1 complement component 5a receptor 1
CES2 carboxylesterase 2
CLEC7A C-type lectin domain family 7, member A
CTBS chitobiase, di-N-acetyl-
CTSE cathepsin E
CXCL10 chemokine (C-X-C motif) ligand 10
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPYD dihydropyrimidine dehydrogenase
DSP desmoplakin
DYNLT3 dynein, light chain, Tctex-type 3
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FAM107A family with sequence similarity 107, member A
FGR FGR proto-oncogene, Src family tyrosine kinase
FN1 fibronectin 1
FPR1 formyl peptide receptor 1
GBP2 guanylate binding protein 2, interferon-inducible
GNAS GNAS complex locus
GRB10 growth factor receptor-bound protein 10
HDGFRP3 hepatoma-derived growth factor, related protein 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HOPX HOP homeobox
HPCAL1 hippocalcin-like 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15 interleukin 15
IPO13 importin 13
KCTD12 potassium channel tetramerization domain containing 12
KRT14 keratin 14, type I
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIMCH1 LIM and calponin homology domains 1
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MSR1 macrophage scavenger receptor 1
MXI1 MAX interactor 1, dimerization protein
N4BP2L1 NEDD4 binding protein 2-like 1
NAMPT nicotinamide phosphoribosyltransferase
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NEBL nebulette
NR2F1 nuclear receptor subfamily 2, group F, member 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PSPH phosphoserine phosphatase
PTPRC protein tyrosine phosphatase, receptor type, C
RGCC regulator of cell cycle
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SNX10 sorting nexin 10
ST18 suppression of tumorigenicity 18, zinc finger
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UBE2B ubiquitin-conjugating enzyme E2B
UFM1 ubiquitin-fold modifier 1
VNN1 vanin 1
WFDC1 WAP four-disulfide core domain 1
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ALCAM activated leukocyte cell adhesion molecule
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANO1 anoctamin 1, calcium activated chloride channel
ANXA6 annexin A6
AURKA aurora kinase A
CA1 carbonic anhydrase I
CARD10 caspase recruitment domain family, member 10
CCNA1 cyclin A1
CCND1 cyclin D1
CD19 CD19 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC20 cell division cycle 20
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DLK1 delta-like 1 homolog (Drosophila)
EZR ezrin
F3 coagulation factor III (thromboplastin, tissue factor)
FADS2 fatty acid desaturase 2
FRZB frizzled-related protein
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GREM1 gremlin 1, DAN family BMP antagonist
GRWD1 glutamate-rich WD repeat containing 1
HBD hemoglobin, delta
HMGB2 high mobility group box 2
HNRNPL heterogeneous nuclear ribonucleoprotein L
HOXC6 homeobox C6
LGALS1 lectin, galactoside-binding, soluble, 1
MATN2 matrilin 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NEK2 NIMA-related kinase 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5E 5'-nucleotidase, ecto (CD73)
NUP98 nucleoporin 98kDa
ODC1 ornithine decarboxylase 1
OSBPL10 oxysterol binding protein-like 10
PARP2 poly (ADP-ribose) polymerase 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK1 polo-like kinase 1
PNN pinin, desmosome associated protein
PROM1 prominin 1
PTCH1 patched 1
RAD23B RAD23 homolog B (S. cerevisiae)
RCAN2 regulator of calcineurin 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOBTB3 Rho-related BTB domain containing 3
S100P S100 calcium binding protein P
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SRSF6 serine/arginine-rich splicing factor 6
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TESC tescalcin
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TMX4 thioredoxin-related transmembrane protein 4
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
VCAN versican