BRD-K10882151_BO2 (inhibits RAD51)_A375_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K10882151_BO2 (inhibits RAD51)_A375_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CYB5R1 cytochrome b5 reductase 1
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP1 dual specificity phosphatase 1
GSTA1 glutathione S-transferase alpha 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IFI27 interferon, alpha-inducible protein 27
IGL immunoglobulin lambda locus
ISG15 ISG15 ubiquitin-like modifier
MAST4 microtubule associated serine/threonine kinase family member 4
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PIR pirin (iron-binding nuclear protein)
PSPH phosphoserine phosphatase
PTPRO protein tyrosine phosphatase, receptor type, O
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
AURKA aurora kinase A
BAMBI BMP and activin membrane-bound inhibitor
CCNA2 cyclin A2
CENPA centromere protein A
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IRS2 insulin receptor substrate 2
LAMB1 laminin, beta 1
LEF1 lymphoid enhancer-binding factor 1
LUC7L3 LUC7-like 3 (S. cerevisiae)
MID1 midline 1
MOK MOK protein kinase
NRIP1 nuclear receptor interacting protein 1
NUSAP1 nucleolar and spindle associated protein 1
SDC2 syndecan 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TOP2A topoisomerase (DNA) II alpha 170kDa