BRD-K10705233_GW405833 hydrochloride_VCAP_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K10705233_GW405833 hydrochloride_VCAP_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTG2 actin, gamma 2, smooth muscle, enteric
C10ORF10 chromosome 10 open reading frame 10
CDK14 cyclin-dependent kinase 14
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL11A1 collagen, type XI, alpha 1
CST1 cystatin SN
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDS iduronate 2-sulfatase
IGFBP3 insulin-like growth factor binding protein 3
INHBA inhibin, beta A
INHBB inhibin, beta B
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
KRT23 keratin 23, type I
KRT7 keratin 7, type II
KRT81 keratin 81, type II
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
NREP neuronal regeneration related protein
NUPR1 nuclear protein, transcriptional regulator, 1
PLA2G16 phospholipase A2, group XVI
RAB31 RAB31, member RAS oncogene family
SGCE sarcoglycan, epsilon
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SST somatostatin
STC1 stanniocalcin 1
TMPRSS3 transmembrane protease, serine 3
VAT1 vesicle amine transport 1
VGLL4 vestigial-like family member 4

decreased expression

Symbol Name
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BK histone cluster 1, H2bk
MCM5 minichromosome maintenance complex component 5
PRKCB protein kinase C, beta