BRD-K10705233_GW405833 hydrochloride_HCC515_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K10705233_GW405833 hydrochloride_HCC515_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACBD3 acyl-CoA binding domain containing 3
ADCK3 aarF domain containing kinase 3
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF3 activating transcription factor 3
BTG2 BTG family, member 2
C1R complement component 1, r subcomponent
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHIC2 cysteine-rich hydrophobic domain 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
FOSL1 FOS-like antigen 1
GFPT1 glutamine--fructose-6-phosphate transaminase 1
HECA headcase homolog (Drosophila)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGA1 high mobility group AT-hook 1
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
JUN jun proto-oncogene
KDM5D lysine (K)-specific demethylase 5D
KYNU kynureninase
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NR4A1 nuclear receptor subfamily 4, group A, member 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLAUR plasminogen activator, urokinase receptor
PTX3 pentraxin 3, long
RPS4Y1 ribosomal protein S4, Y-linked 1
RRAGD Ras-related GTP binding D
SMAD1 SMAD family member 1
SOD2 superoxide dismutase 2, mitochondrial
SSBP2 single-stranded DNA binding protein 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNPO1 transportin 1

decreased expression

Symbol Name
CCND1 cyclin D1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GADD45B growth arrest and DNA-damage-inducible, beta
KRT14 keratin 14, type I
KRT5 keratin 5, type II
LAMP5 lysosomal-associated membrane protein family, member 5
MCM3 minichromosome maintenance complex component 3
MSH6 mutS homolog 6
PLK1 polo-like kinase 1
S100A10 S100 calcium binding protein A10
SFN stratifin
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
XIST X inactive specific transcript (non-protein coding)