BRD-K10177585_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K10177585_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BTG3 BTG family, member 3
CD9 CD9 molecule
CHMP4A charged multivesicular body protein 4A
EGFR epidermal growth factor receptor
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GATA3 GATA binding protein 3
GLS glutaminase
GPM6B glycoprotein M6B
HES1 hes family bHLH transcription factor 1
HMG20B high mobility group 20B
JCHAIN joining chain of multimeric IgA and IgM
KRT17 keratin 17, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MLPH melanophilin
NEO1 neogenin 1
PEA15 phosphoprotein enriched in astrocytes 15
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PTN pleiotrophin
SCGB1D2 secretoglobin, family 1D, member 2
STS steroid sulfatase (microsomal), isozyme S
TSPAN12 tetraspanin 12
VTCN1 V-set domain containing T cell activation inhibitor 1
WBP5 WW domain binding protein 5

decreased expression

Symbol Name
ASPN asporin
CCND2 cyclin D2
CCR2 chemokine (C-C motif) receptor 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLIC3 chloride intracellular channel 3
CXCL12 chemokine (C-X-C motif) ligand 12
DMD dystrophin
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5A eukaryotic translation initiation factor 5A
ELL2 elongation factor, RNA polymerase II, 2
EPHA3 EPH receptor A3
GAS1 growth arrest-specific 1
GNAS GNAS complex locus
HOXC6 homeobox C6
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KCTD12 potassium channel tetramerization domain containing 12
KLF4 Kruppel-like factor 4 (gut)
MARCKS myristoylated alanine-rich protein kinase C substrate
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PEG3 paternally expressed 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLBD1 phospholipase B domain containing 1
PSPH phosphoserine phosphatase
RPL31 ribosomal protein L31
SEPP1 selenoprotein P, plasma, 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SMA4 glucuronidase, beta pseudogene
SOX11 SRY (sex determining region Y)-box 11
SPRR2B small proline-rich protein 2B
SRSF6 serine/arginine-rich splicing factor 6
STOM stomatin
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS2 thrombospondin 2
ZNF586 zinc finger protein 586