BRD-K09991945_GSK-3-inhibitor-II_HT29_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K09991945_GSK-3-inhibitor-II_HT29_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AGR2 anterior gradient 2
ANO10 anoctamin 10
AREG amphiregulin
BPHL biphenyl hydrolase-like (serine hydrolase)
CCL4 chemokine (C-C motif) ligand 4
CCND1 cyclin D1
CD3D CD3d molecule, delta (CD3-TCR complex)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DSP desmoplakin
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPCAM epithelial cell adhesion molecule
FGFR3 fibroblast growth factor receptor 3
GDF15 growth differentiation factor 15
GLDC glycine dehydrogenase (decarboxylating)
GOLM1 golgi membrane protein 1
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HN1 hematological and neurological expressed 1
ICAM1 intercellular adhesion molecule 1
IGLV2-23 immunoglobulin lambda variable 2-23
IL32 interleukin 32
IL6R interleukin 6 receptor
ISOC1 isochorismatase domain containing 1
NAP1L3 nucleosome assembly protein 1-like 3
PNMA1 paraneoplastic Ma antigen 1
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTCH1 patched 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGS1 regulator of G-protein signaling 1
RHOF ras homolog family member F (in filopodia)
SEPP1 selenoprotein P, plasma, 1
SH2D1A SH2 domain containing 1A
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SPINK1 serine peptidase inhibitor, Kazal type 1
TFRC transferrin receptor
TM4SF1 transmembrane 4 L six family member 1
TM9SF3 transmembrane 9 superfamily member 3
TP53 tumor protein p53
TRBC1 T cell receptor beta constant 1
VAMP8 vesicle-associated membrane protein 8
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ADM adrenomedullin
APOD apolipoprotein D
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BLNK B-cell linker
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV1 caveolin 1, caveolae protein, 22kDa
CLCA2 chloride channel accessory 2
CNN3 calponin 3, acidic
CRELD2 cysteine-rich with EGF-like domains 2
CSTA cystatin A (stefin A)
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
FAM129A family with sequence similarity 129, member A
GJA1 gap junction protein, alpha 1, 43kDa
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DRA major histocompatibility complex, class II, DR alpha
HOXC6 homeobox C6
IFI16 interferon, gamma-inducible protein 16
IFI44 interferon-induced protein 44
IPO13 importin 13
KIAA0226L KIAA0226-like
KLK5 kallikrein-related peptidase 5
LOX lysyl oxidase
LRMP lymphoid-restricted membrane protein
MEIS2 Meis homeobox 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NSG1 neuron specific gene family member 1
OSBPL10 oxysterol binding protein-like 10
PAX5 paired box 5
PBX3 pre-B-cell leukemia homeobox 3
PCP4 Purkinje cell protein 4
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRUNE2 prune homolog 2 (Drosophila)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RNH1 ribonuclease/angiogenin inhibitor 1
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SHB Src homology 2 domain containing adaptor protein B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STC1 stanniocalcin 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TPM2 tropomyosin 2 (beta)
TRIB2 tribbles pseudokinase 2
TRIM2 tripartite motif containing 2
UGCG UDP-glucose ceramide glucosyltransferase
VPREB3 pre-B lymphocyte 3
ZNF395 zinc finger protein 395