BRD-K09991945_GSK-3-inhibitor-II_HEPG2_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K09991945_GSK-3-inhibitor-II_HEPG2_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACBD3 acyl-CoA binding domain containing 3
ADIRF adipogenesis regulatory factor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
BMP2 bone morphogenetic protein 2
CLIC3 chloride intracellular channel 3
CLU clusterin
CPNE3 copine III
CRYAB crystallin, alpha B
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYBA cytochrome b-245, alpha polypeptide
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FHL1 four and a half LIM domains 1
FOXC1 forkhead box C1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HOPX HOP homeobox
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
KANK1 KN motif and ankyrin repeat domains 1
KAZN kazrin, periplakin interacting protein
LTF lactotransferrin
MAP7 microtubule-associated protein 7
MGP matrix Gla protein
NEBL nebulette
PLAC8 placenta-specific 8
PPARG peroxisome proliferator-activated receptor gamma
SPP1 secreted phosphoprotein 1
STOM stomatin
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBX3 T-box 3
TFF1 trefoil factor 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF586 zinc finger protein 586
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BCHE butyrylcholinesterase
BIRC3 baculoviral IAP repeat containing 3
CD44 CD44 molecule (Indian blood group)
CDK4 cyclin-dependent kinase 4
CLDN8 claudin 8
CTSH cathepsin H
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHCR24 24-dehydrocholesterol reductase
DPT dermatopontin
FAM69A family with sequence similarity 69, member A
FGG fibrinogen gamma chain
HIST1H2BC histone cluster 1, H2bc
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IER5 immediate early response 5
IGFBP1 insulin-like growth factor binding protein 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV2-23 immunoglobulin lambda variable 2-23
JCHAIN joining chain of multimeric IgA and IgM
KRT19 keratin 19, type I
LBP lipopolysaccharide binding protein
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LY6H lymphocyte antigen 6 complex, locus H
MARCKS myristoylated alanine-rich protein kinase C substrate
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MS4A12 membrane-spanning 4-domains, subfamily A, member 12
NSG1 neuron specific gene family member 1
ORC1 origin recognition complex, subunit 1
PLAU plasminogen activator, urokinase
POSTN periostin, osteoblast specific factor
POU2AF1 POU class 2 associating factor 1
PPOX protoporphyrinogen oxidase
RBP1 retinol binding protein 1, cellular
SOX11 SRY (sex determining region Y)-box 11
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
TMEM45A transmembrane protein 45A
TUBA1A tubulin, alpha 1a
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
VCAN versican