BRD-K09991945_GSK-3-inhibitor-II_HA1E_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K09991945_GSK-3-inhibitor-II_HA1E_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BPHL biphenyl hydrolase-like (serine hydrolase)
CD9 CD9 molecule
CLGN calmegin
CREM cAMP responsive element modulator
CYFIP2 cytoplasmic FMR1 interacting protein 2
GGCX gamma-glutamyl carboxylase
IGHD immunoglobulin heavy constant delta
LGSN lengsin, lens protein with glutamine synthetase domain
MMP10 matrix metallopeptidase 10
NKX3-1 NK3 homeobox 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PIR pirin (iron-binding nuclear protein)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRAME preferentially expressed antigen in melanoma
PTHLH parathyroid hormone-like hormone
RGCC regulator of cell cycle
STK17B serine/threonine kinase 17b
STK26 serine/threonine protein kinase 26
TCL1A T-cell leukemia/lymphoma 1A
TUBB2A tubulin, beta 2A class IIa
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)
ZBTB18 zinc finger and BTB domain containing 18
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACAA2 acetyl-CoA acyltransferase 2
ADAM12 ADAM metallopeptidase domain 12
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AQP1 aquaporin 1 (Colton blood group)
ARG1 arginase 1
C3 complement component 3
CD24 CD24 molecule
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CXCL12 chemokine (C-X-C motif) ligand 12
DCN decorin
DEPTOR DEP domain containing MTOR-interacting protein
DHCR24 24-dehydrocholesterol reductase
DLC1 DLC1 Rho GTPase activating protein
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
FBN1 fibrillin 1
FHL1 four and a half LIM domains 1
FLRT2 fibronectin leucine rich transmembrane protein 2
G0S2 G0/G1 switch 2
GAL galanin/GMAP prepropeptide
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLUL glutamate-ammonia ligase
GPX3 glutathione peroxidase 3
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
ITM2A integral membrane protein 2A
KRT6B keratin 6B, type II
LOX lysyl oxidase
LPIN1 lipin 1
LYZ lysozyme
MAN1A1 mannosidase, alpha, class 1A, member 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
METTL7A methyltransferase like 7A
MFAP4 microfibrillar-associated protein 4
MRPS2 mitochondrial ribosomal protein S2
MT1M metallothionein 1M
NDN necdin, melanoma antigen (MAGE) family member
NID2 nidogen 2 (osteonidogen)
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PCOLCE procollagen C-endopeptidase enhancer
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLBD1 phospholipase B domain containing 1
PPIC peptidylprolyl isomerase C (cyclophilin C)
PROM1 prominin 1
PRSS3 protease, serine, 3
PTCH1 patched 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
SDC2 syndecan 2
SNAI2 snail family zinc finger 2
STOM stomatin
TCF4 transcription factor 4
TLE4 transducin-like enhancer of split 4
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15