BRD-K09991945_GSK-3 Inhibitor II_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

23 genes differentially expressed following the BRD-K09991945_GSK-3 Inhibitor II_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ASNS asparagine synthetase (glutamine-hydrolyzing)
CAV1 caveolin 1, caveolae protein, 22kDa
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
IDO1 indoleamine 2,3-dioxygenase 1
INSIG1 insulin induced gene 1
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
JUN jun proto-oncogene
PEG10 paternally expressed 10
PQBP1 polyglutamine binding protein 1
PSPH phosphoserine phosphatase
SGCE sarcoglycan, epsilon
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)

decreased expression

Symbol Name
CA2 carbonic anhydrase II
DHRS3 dehydrogenase/reductase (SDR family) member 3
GALC galactosylceramidase
HK1 hexokinase 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
S100P S100 calcium binding protein P
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSPAN31 tetraspanin 31
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)