BRD-K09991945_GSK-3 Inhibitor II_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K09991945_GSK-3 Inhibitor II_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASCL1 achaete-scute family bHLH transcription factor 1
BEX1 brain expressed, X-linked 1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHRDL1 chordin-like 1
CXCL14 chemokine (C-X-C motif) ligand 14
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM107A family with sequence similarity 107, member A
FKBP1B FK506 binding protein 1B, 12.6 kDa
LDLR low density lipoprotein receptor
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MFAP5 microfibrillar associated protein 5
MT1E metallothionein 1E
MT1M metallothionein 1M
PPAP2B phosphatidic acid phosphatase type 2B
PROM1 prominin 1
PSAT1 phosphoserine aminotransferase 1
RET ret proto-oncogene
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TSC22D3 TSC22 domain family, member 3
TSPAN8 tetraspanin 8
TXNDC9 thioredoxin domain containing 9

decreased expression

Symbol Name
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
AREG amphiregulin
CD24 CD24 molecule
GATA3 GATA binding protein 3
GNLY granulysin
HSPH1 heat shock 105kDa/110kDa protein 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
MME membrane metallo-endopeptidase
MYO6 myosin VI
SCGB1D2 secretoglobin, family 1D, member 2
SMAD3 SMAD family member 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TTC3 tetratricopeptide repeat domain 3