BRD-K09907482_PRL-3 Inhibitor I_PC3_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K09907482_PRL-3 Inhibitor I_PC3_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACADVL acyl-CoA dehydrogenase, very long chain
ADRB2 adrenoceptor beta 2, surface
ANGPTL4 angiopoietin-like 4
ASNS asparagine synthetase (glutamine-hydrolyzing)
CA12 carbonic anhydrase XII
CCL20 chemokine (C-C motif) ligand 20
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CSTA cystatin A (stefin A)
DDIT4 DNA-damage-inducible transcript 4
FBLN1 fibulin 1
GPM6B glycoprotein M6B
HMOX1 heme oxygenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
ITGB5 integrin, beta 5
IVL involucrin
JUN jun proto-oncogene
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KLF5 Kruppel-like factor 5 (intestinal)
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT6A keratin 6A, type II
LGALS2 lectin, galactoside-binding, soluble, 2
MAN1A1 mannosidase, alpha, class 1A, member 1
MAST2 microtubule associated serine/threonine kinase 2
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1M metallothionein 1M
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NDRG1 N-myc downstream regulated 1
PCSK5 proprotein convertase subtilisin/kexin type 5
PDLIM4 PDZ and LIM domain 4
PLAU plasminogen activator, urokinase
PPARD peroxisome proliferator-activated receptor delta
PRKCD protein kinase C, delta
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFN stratifin
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TNFRSF21 tumor necrosis factor receptor superfamily, member 21

decreased expression

Symbol Name
AGR2 anterior gradient 2
ANXA5 annexin A5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CKAP4 cytoskeleton-associated protein 4
CYR61 cysteine-rich, angiogenic inducer, 61
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
ELOVL5 ELOVL fatty acid elongase 5
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ETV1 ets variant 1
FBP1 fructose-1,6-bisphosphatase 1
HOXA10 homeobox A10
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
LIPA lipase A, lysosomal acid, cholesterol esterase
NEBL nebulette
NPTX2 neuronal pentraxin II
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PEG10 paternally expressed 10
PIP prolactin-induced protein
PRSS23 protease, serine, 23
RPS11 ribosomal protein S11
SCGB2A2 secretoglobin, family 2A, member 2
SFTPA2 surfactant protein A2
STMN1 stathmin 1
TMEM255A transmembrane protein 255A