BRD-K09907482_PRL-3 Inhibitor I_HT29_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-K09907482_PRL-3 Inhibitor I_HT29_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CD24 CD24 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
ELANE elastase, neutrophil expressed
ELOVL6 ELOVL fatty acid elongase 6
FOLR1 folate receptor 1 (adult)
GRB14 growth factor receptor-bound protein 14
HMOX1 heme oxygenase 1
HOXC6 homeobox C6
IRS1 insulin receptor substrate 1
MT2A metallothionein 2A
NPY neuropeptide Y
SELL selectin L
SQSTM1 sequestosome 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
ATP2A3 ATPase, Ca++ transporting, ubiquitous
HOPX HOP homeobox
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
LIMCH1 LIM and calponin homology domains 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCDH17 protocadherin 17
RTN2 reticulon 2
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SRGN serglycin
TSPAN12 tetraspanin 12