BRD-K09299610_4-(6-methoxynaphthalen-2-yl)-N,N-diphenyl-1H-1,2,3-triazole-1-carboxamide_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K09299610_4-(6-methoxynaphthalen-2-yl)-N,N-diphenyl-1H-1,2,3-triazole-1-carboxamide_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CALR calreticulin
CCL20 chemokine (C-C motif) ligand 20
CCR2 chemokine (C-C motif) receptor 2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CETN2 centrin, EF-hand protein, 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
FABP6 fatty acid binding protein 6, ileal
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXB2 homeobox B2
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LEF1 lymphoid enhancer-binding factor 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MEG3 maternally expressed 3 (non-protein coding)
MSMO1 methylsterol monooxygenase 1
NFE2L2 nuclear factor, erythroid 2-like 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
QPCT glutaminyl-peptide cyclotransferase
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQLE squalene epoxidase
THBS2 thrombospondin 2
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
BST2 bone marrow stromal cell antigen 2
C8ORF4 chromosome 8 open reading frame 4
CCNF cyclin F
CLEC2B C-type lectin domain family 2, member B
CLU clusterin
IFITM2 interferon induced transmembrane protein 2
PRPF4 pre-mRNA processing factor 4
RBPMS RNA binding protein with multiple splicing
SPATA20 spermatogenesis associated 20
STOM stomatin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TM4SF1 transmembrane 4 L six family member 1
USP1 ubiquitin specific peptidase 1