BRD-K09299610_4-(6-methoxynaphthalen-2-yl)-N,N-diphenyl-1H-1,2,3-triazole-1-carboxamide_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

23 genes differentially expressed following the BRD-K09299610_4-(6-methoxynaphthalen-2-yl)-N,N-diphenyl-1H-1,2,3-triazole-1-carboxamide_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
FGFR3 fibroblast growth factor receptor 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
METRN meteorin, glial cell differentiation regulator
PDLIM1 PDZ and LIM domain 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SPAG4 sperm associated antigen 4
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CKAP4 cytoskeleton-associated protein 4
COL5A2 collagen, type V, alpha 2
CPE carboxypeptidase E
CRABP1 cellular retinoic acid binding protein 1
DEPTOR DEP domain containing MTOR-interacting protein
DKK3 dickkopf WNT signaling pathway inhibitor 3
EPB41L3 erythrocyte membrane protein band 4.1-like 3
HSPA1A heat shock 70kDa protein 1A
MUC2 mucin 2, oligomeric mucus/gel-forming
PBX1 pre-B-cell leukemia homeobox 1
TFPI2 tissue factor pathway inhibitor 2