BRD-K08714182_SERICETIN DIMETHYL ETHER_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

194 genes differentially expressed following the BRD-K08714182_SERICETIN DIMETHYL ETHER_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDOC aldolase C, fructose-bisphosphate
ANPEP alanyl (membrane) aminopeptidase
ANXA2 annexin A2
APOD apolipoprotein D
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASRGL1 asparaginase like 1
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
BIN1 bridging integrator 1
CAPG capping protein (actin filament), gelsolin-like
CBR3 carbonyl reductase 3
CCNG2 cyclin G2
CD36 CD36 molecule (thrombospondin receptor)
CES1 carboxylesterase 1
CHRDL1 chordin-like 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC2B C-type lectin domain family 2, member B
COL6A3 collagen, type VI, alpha 3
COL9A3 collagen, type IX, alpha 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CXCL12 chemokine (C-X-C motif) ligand 12
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DES desmin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
EFS embryonal Fyn-associated substrate
EML3 echinoderm microtubule associated protein like 3
ERBB3 erb-b2 receptor tyrosine kinase 3
FBLN1 fibulin 1
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FMO5 flavin containing monooxygenase 5
FXYD1 FXYD domain containing ion transport regulator 1
FZD2 frizzled class receptor 2
GATA3 GATA binding protein 3
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPER1 G protein-coupled estrogen receptor 1
GTSE1 G-2 and S-phase expressed 1
H1FX H1 histone family, member X
HDC histidine decarboxylase
HEBP2 heme binding protein 2
HLA-B major histocompatibility complex, class I, B
HSPB8 heat shock 22kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ILK integrin-linked kinase
IRF9 interferon regulatory factor 9
KIAA1033 KIAA1033
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
MICB MHC class I polypeptide-related sequence B
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MOXD1 monooxygenase, DBH-like 1
MX1 MX dynamin-like GTPase 1
NOTCH2 notch 2
NQO1 NAD(P)H dehydrogenase, quinone 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OSR2 odd-skipped related transciption factor 2
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PERP PERP, TP53 apoptosis effector
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLK1 polo-like kinase 1
PNKP polynucleotide kinase 3'-phosphatase
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RBPMS RNA binding protein with multiple splicing
REG1B regenerating islet-derived 1 beta
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOB ras homolog family member B
S100A10 S100 calcium binding protein A10
S100A11 S100 calcium binding protein A11
S100A13 S100 calcium binding protein A13
S100A6 S100 calcium binding protein A6
SCARB2 scavenger receptor class B, member 2
SDPR serum deprivation response
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SMTN smoothelin
SNN stannin
SRPX sushi-repeat containing protein, X-linked
TCTA T-cell leukemia translocation altered
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TMPO thymopoietin
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1
TUBA1A tubulin, alpha 1a
TUBB6 tubulin, beta 6 class V
WEE1 WEE1 G2 checkpoint kinase
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP1 A kinase (PRKA) anchor protein 1
ASCC3 activating signal cointegrator 1 complex subunit 3
ATP9A ATPase, class II, type 9A
ATXN1 ataxin 1
BBX bobby sox homolog (Drosophila)
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BGN biglycan
C1QBP complement component 1, q subcomponent binding protein
CA1 carbonic anhydrase I
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASP7 caspase 7, apoptosis-related cysteine peptidase
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK14 cyclin-dependent kinase 14
CFI complement factor I
COL5A2 collagen, type V, alpha 2
CP ceruloplasmin (ferroxidase)
CREM cAMP responsive element modulator
CRTAP cartilage associated protein
CTNND1 catenin (cadherin-associated protein), delta 1
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPH2 DPH2 homolog (S. cerevisiae)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
EIF4A1 eukaryotic translation initiation factor 4A1
EIF5A eukaryotic translation initiation factor 5A
FKBP11 FK506 binding protein 11, 19 kDa
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GOLGA4 golgin A4
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IARS isoleucyl-tRNA synthetase
IGF1R insulin-like growth factor 1 receptor
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
KDM5D lysine (K)-specific demethylase 5D
KIF5C kinesin family member 5C
KRT23 keratin 23, type I
LAMA3 laminin, alpha 3
LEF1 lymphoid enhancer-binding factor 1
LOC100272216 uncharacterized LOC100272216
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP2K5 mitogen-activated protein kinase kinase 5
MAST4 microtubule associated serine/threonine kinase family member 4
MECOM MDS1 and EVI1 complex locus
METRN meteorin, glial cell differentiation regulator
MINK1 misshapen-like kinase 1
MME membrane metallo-endopeptidase
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH10 myosin, heavy chain 10, non-muscle
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NELL2 NEL-like 2 (chicken)
NME1 NME/NM23 nucleoside diphosphate kinase 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5DC2 5'-nucleotidase domain containing 2
NUDCD3 NudC domain containing 3
PEG3 paternally expressed 3
PFKP phosphofructokinase, platelet
PPIF peptidylprolyl isomerase F
PTK2 protein tyrosine kinase 2
PUS7 pseudouridylate synthase 7 (putative)
PYCR1 pyrroline-5-carboxylate reductase 1
QKI QKI, KH domain containing, RNA binding
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL22 ribosomal protein L22
RPL31 ribosomal protein L31
RPS21 ribosomal protein S21
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCARB1 scavenger receptor class B, member 1
SERINC5 serine incorporator 5
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SRI sorcin
ST7 suppression of tumorigenicity 7
STAR steroidogenic acute regulatory protein
TBC1D16 TBC1 domain family, member 16
TEX10 testis expressed 10
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TRIM29 tripartite motif containing 29
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TTC3 tetratricopeptide repeat domain 3
WDTC1 WD and tetratricopeptide repeats 1
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF331 zinc finger protein 331