BRD-K08714182_SERICETIN DIMETHYL ETHER_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

131 genes differentially expressed following the BRD-K08714182_SERICETIN DIMETHYL ETHER_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG1 adhesion G protein-coupled receptor G1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APOD apolipoprotein D
AQP3 aquaporin 3 (Gill blood group)
CCL5 chemokine (C-C motif) ligand 5
CDC25B cell division cycle 25B
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
COL3A1 collagen, type III, alpha 1
CPE carboxypeptidase E
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTGF connective tissue growth factor
CXCL14 chemokine (C-X-C motif) ligand 14
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DCN decorin
DUSP1 dual specificity phosphatase 1
E2F2 E2F transcription factor 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FLNA filamin A, alpha
FZD2 frizzled class receptor 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GADD45B growth arrest and DNA-damage-inducible, beta
GPX3 glutathione peroxidase 3
HOPX HOP homeobox
HOXC10 homeobox C10
HOXC6 homeobox C6
HSPB8 heat shock 22kDa protein 8
ICAM1 intercellular adhesion molecule 1
KRT7 keratin 7, type II
KYNU kynureninase
LGALS1 lectin, galactoside-binding, soluble, 1
MAOA monoamine oxidase A
MICB MHC class I polypeptide-related sequence B
MKNK2 MAP kinase interacting serine/threonine kinase 2
MUC1 mucin 1, cell surface associated
MYL9 myosin, light chain 9, regulatory
NOV nephroblastoma overexpressed
OASL 2'-5'-oligoadenylate synthetase-like
PDLIM2 PDZ and LIM domain 2 (mystique)
POSTN periostin, osteoblast specific factor
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
S100A10 S100 calcium binding protein A10
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIX2 SIX homeobox 2
SOBP sine oculis binding protein homolog (Drosophila)
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
TAGLN transgelin
TGFA transforming growth factor, alpha
TGFBR3 transforming growth factor, beta receptor III
THBS4 thrombospondin 4
TSC22D3 TSC22 domain family, member 3
TSPYL5 TSPY-like 5
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
AGR2 anterior gradient 2
ANO10 anoctamin 10
ARL4C ADP-ribosylation factor-like 4C
ASCC3 activating signal cointegrator 1 complex subunit 3
ATP9A ATPase, class II, type 9A
AUTS2 autism susceptibility candidate 2
CA12 carbonic anhydrase XII
CD200 CD200 molecule
CD69 CD69 molecule
CERS6 ceramide synthase 6
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
EFNB2 ephrin-B2
EPHB2 EPH receptor B2
EVL Enah/Vasp-like
FAM171A1 family with sequence similarity 171, member A1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GATA6 GATA binding protein 6
GPC4 glypican 4
GPX1 glutathione peroxidase 1
GRB10 growth factor receptor-bound protein 10
GSTO1 glutathione S-transferase omega 1
GSTP1 glutathione S-transferase pi 1
HEPH hephaestin
HK2 hexokinase 2
HP haptoglobin
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
ITGA6 integrin, alpha 6
ITGB4 integrin, beta 4
JCHAIN joining chain of multimeric IgA and IgM
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LAMA3 laminin, alpha 3
LAPTM5 lysosomal protein transmembrane 5
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LRRC16A leucine rich repeat containing 16A
LYZ lysozyme
MAP7 microtubule-associated protein 7
MME membrane metallo-endopeptidase
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH10 myosin, heavy chain 10, non-muscle
MYRF myelin regulatory factor
PDZRN3 PDZ domain containing ring finger 3
PFKL phosphofructokinase, liver
PGK1 phosphoglycerate kinase 1
RPS11 ribosomal protein S11
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOX4 SRY (sex determining region Y)-box 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRGN serglycin
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TFRC transferrin receptor
TIAM1 T-cell lymphoma invasion and metastasis 1
TOX3 TOX high mobility group box family member 3
TRAF5 TNF receptor-associated factor 5
VGLL4 vestigial-like family member 4
XBP1 X-box binding protein 1
ZMIZ1 zinc finger, MIZ-type containing 1