BRD-K08589866_OSI-906_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K08589866_OSI-906_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
APOD apolipoprotein D
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCNG2 cyclin G2
CD36 CD36 molecule (thrombospondin receptor)
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPA3 carboxypeptidase A3 (mast cell)
DCLK1 doublecortin-like kinase 1
EFHD1 EF-hand domain family, member D1
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM63A family with sequence similarity 63, member A
GRN granulin
GSTM3 glutathione S-transferase mu 3 (brain)
HBP1 HMG-box transcription factor 1
HIST1H2AC histone cluster 1, H2ac
HMOX1 heme oxygenase 1
IGF1R insulin-like growth factor 1 receptor
IRS2 insulin receptor substrate 2
JAG1 jagged 1
KDM3A lysine (K)-specific demethylase 3A
KDM5D lysine (K)-specific demethylase 5D
LMO3 LIM domain only 3 (rhombotin-like 2)
LXN latexin
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NEBL nebulette
PBX1 pre-B-cell leukemia homeobox 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
S100A8 S100 calcium binding protein A8
SEPP1 selenoprotein P, plasma, 1
SFRP1 secreted frizzled-related protein 1
SLC16A4 solute carrier family 16, member 4
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
TPP1 tripeptidyl peptidase I
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CDC42 cell division cycle 42
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FBXL12 F-box and leucine-rich repeat protein 12
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
JMJD6 jumonji domain containing 6
LDHB lactate dehydrogenase B
RUFY3 RUN and FYVE domain containing 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TSPAN8 tetraspanin 8