BRD-K08589866_OSI-906_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

171 genes differentially expressed following the BRD-K08589866_OSI-906_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ACSL5 acyl-CoA synthetase long-chain family member 5
ADGRF5 adhesion G protein-coupled receptor F5
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
ANXA4 annexin A4
ARMCX1 armadillo repeat containing, X-linked 1
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BEX4 brain expressed, X-linked 4
BGN biglycan
BHLHE41 basic helix-loop-helix family, member e41
C10ORF10 chromosome 10 open reading frame 10
C14ORF132 chromosome 14 open reading frame 132
C1ORF106 chromosome 1 open reading frame 106
C6ORF62 chromosome 6 open reading frame 62
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC5 chloride intracellular channel 5
CP ceruloplasmin (ferroxidase)
CRABP2 cellular retinoic acid binding protein 2
CTGF connective tissue growth factor
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK5 docking protein 5
DPYSL2 dihydropyrimidinase-like 2
DPYSL3 dihydropyrimidinase-like 3
EDN1 endothelin 1
EFNA1 ephrin-A1
EGFL6 EGF-like-domain, multiple 6
EPS8L3 EPS8-like 3
ERBB3 erb-b2 receptor tyrosine kinase 3
FABP4 fatty acid binding protein 4, adipocyte
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FILIP1L filamin A interacting protein 1-like
FOXO4 forkhead box O4
GAS6 growth arrest-specific 6
GNB5 guanine nucleotide binding protein (G protein), beta 5
GREM1 gremlin 1, DAN family BMP antagonist
GSN gelsolin
HOXD1 homeobox D1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI6 interferon, alpha-inducible protein 6
IRS2 insulin receptor substrate 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
LBH limb bud and heart development
LGALS8 lectin, galactoside-binding, soluble, 8
LXN latexin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOA monoamine oxidase A
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MECOM MDS1 and EVI1 complex locus
MGLL monoglyceride lipase
MSLN mesothelin
MVP major vault protein
NDRG1 N-myc downstream regulated 1
NPDC1 neural proliferation, differentiation and control, 1
NSG1 neuron specific gene family member 1
OPHN1 oligophrenin 1
OPTN optineurin
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAWR PRKC, apoptosis, WT1, regulator
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDZD2 PDZ domain containing 2
PRSS23 protease, serine, 23
PRUNE2 prune homolog 2 (Drosophila)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAP1GAP RAP1 GTPase activating protein
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle
RND3 Rho family GTPase 3
RPL37A ribosomal protein L37a
SCG5 secretogranin V
SCGB2A1 secretoglobin, family 2A, member 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SFRP4 secreted frizzled-related protein 4
SKAP2 src kinase associated phosphoprotein 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINT1 serine peptidase inhibitor, Kunitz type 1
SRI sorcin
SST somatostatin
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOX thymocyte selection-associated high mobility group box
TP53I3 tumor protein p53 inducible protein 3
TRAF5 TNF receptor-associated factor 5
TRAPPC6A trafficking protein particle complex 6A
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIB2 tribbles pseudokinase 2
TRIM22 tripartite motif containing 22
TUBA1A tubulin, alpha 1a
WDR45 WD repeat domain 45
WDTC1 WD and tetratricopeptide repeats 1
ZC2HC1A zinc finger, C2HC-type containing 1A
ZFPM2 zinc finger protein, FOG family member 2
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
AMD1 adenosylmethionine decarboxylase 1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AURKA aurora kinase A
BCLAF1 BCL2-associated transcription factor 1
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
CCNA2 cyclin A2
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CHSY1 chondroitin sulfate synthase 1
CLTB clathrin, light chain B
COL4A5 collagen, type IV, alpha 5
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CTSC cathepsin C
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DEFB1 defensin, beta 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
ECI2 enoyl-CoA delta isomerase 2
ENOSF1 enolase superfamily member 1
FASTKD5 FAST kinase domains 5
GRB14 growth factor receptor-bound protein 14
GSPT1 G1 to S phase transition 1
HSPA4L heat shock 70kDa protein 4-like
IL6ST interleukin 6 signal transducer
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAPTM4B lysosomal protein transmembrane 4 beta
LMNB2 lamin B2
MCM10 minichromosome maintenance complex component 10
NGRN neugrin, neurite outgrowth associated
NUP98 nucleoporin 98kDa
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PBK PDZ binding kinase
PEX3 peroxisomal biogenesis factor 3
PHGDH phosphoglycerate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLK1 polo-like kinase 1
PPIF peptidylprolyl isomerase F
PRC1 protein regulator of cytokinesis 1
RGS2 regulator of G-protein signaling 2
SACS sacsin molecular chaperone
SHCBP1 SHC SH2-domain binding protein 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SNX11 sorting nexin 11
SORD sorbitol dehydrogenase
TACC3 transforming, acidic coiled-coil containing protein 3
TNC tenascin C
TPX2 TPX2, microtubule-associated
UBE2S ubiquitin-conjugating enzyme E2S
VCAN versican
WDR61 WD repeat domain 61
YES1 YES proto-oncogene 1, Src family tyrosine kinase