BRD-K08438429_NNC 26-9100_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K08438429_NNC 26-9100_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
AMDHD2 amidohydrolase domain containing 2
AQP3 aquaporin 3 (Gill blood group)
BASP1 brain abundant, membrane attached signal protein 1
BCAP31 B-cell receptor-associated protein 31
BMP4 bone morphogenetic protein 4
CAPG capping protein (actin filament), gelsolin-like
CD9 CD9 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHGB chromogranin B
CLEC2B C-type lectin domain family 2, member B
CRABP2 cellular retinoic acid binding protein 2
CRELD2 cysteine-rich with EGF-like domains 2
CXCL11 chemokine (C-X-C motif) ligand 11
DACH1 dachshund family transcription factor 1
ENO2 enolase 2 (gamma, neuronal)
FABP4 fatty acid binding protein 4, adipocyte
FBLN1 fibulin 1
GPR183 G protein-coupled receptor 183
GRN granulin
HLA-B major histocompatibility complex, class I, B
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HOXB2 homeobox B2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INA internexin neuronal intermediate filament protein, alpha
ISG15 ISG15 ubiquitin-like modifier
LAMP3 lysosomal-associated membrane protein 3
MAOA monoamine oxidase A
MLPH melanophilin
MMP7 matrix metallopeptidase 7
NEU1 sialidase 1 (lysosomal sialidase)
OLFM4 olfactomedin 4
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PTGER4 prostaglandin E receptor 4 (subtype EP4)
QPCT glutaminyl-peptide cyclotransferase
RND3 Rho family GTPase 3
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNAP25 synaptosomal-associated protein, 25kDa
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLK2 tousled-like kinase 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADD3 adducin 3 (gamma)
ADGRL2 adhesion G protein-coupled receptor L2
BZW2 basic leucine zipper and W2 domains 2
C7 complement component 7
CADM1 cell adhesion molecule 1
COL15A1 collagen, type XV, alpha 1
CXCL12 chemokine (C-X-C motif) ligand 12
EPCAM epithelial cell adhesion molecule
EPHA3 EPH receptor A3
FBXL12 F-box and leucine-rich repeat protein 12
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPX3 glutathione peroxidase 3
HOMER1 homer scaffolding protein 1
HOXC6 homeobox C6
IGFBP5 insulin-like growth factor binding protein 5
ITM2A integral membrane protein 2A
KIF18B kinesin family member 18B
LAMC1 laminin, gamma 1 (formerly LAMB2)
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MCAM melanoma cell adhesion molecule
METTL7A methyltransferase like 7A
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NFIB nuclear factor I/B
PLK1 polo-like kinase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PPIC peptidylprolyl isomerase C (cyclophilin C)
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SDC2 syndecan 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SOBP sine oculis binding protein homolog (Drosophila)
TAGLN transgelin
TNC tenascin C
TSPAN8 tetraspanin 8
XIST X inactive specific transcript (non-protein coding)